Negative Mood States Correlate with Laterobasal Amygdala in Collegiate Football Players
- 주제(기타) Biotechnology & Applied Microbiology; Medicine, Research & Experimental
- 설명문(일반) [Cho, Han Byul; Bueler, Charles Elliott; DiMuzio, Jennifer; McGlade, Erin; Lyoo, In Kyoon; Yurgelun-Todd, Deborah] Univ Utah, Brain Inst, 383 Colorow Dr, Salt Lake City, UT 84108 USA; [Cho, Han Byul; Bueler, Charles Elliott; DiMuzio, Jennifer; McGlade, Erin; Yurgelun-Todd, Deborah] Univ Utah, Diagnost Neuroimaging Lab, 501 Chipeta Way, Salt Lake City, UT 84108 USA; [Cho, Han Byul; McGlade, Erin; Lyoo, In Kyoon; Yurgelun-Todd, Deborah] Sch Med, Dept Psychiat, 501 Chipeta Way, Salt Lake City, UT 84108 USA; [Hicks-Little, Charlie] Univ Utah, Dept Phys Therapy & Athlet Training, 520 Wakara Way, Salt Lake City, UT 84108 USA; [McGlade, Erin; Yurgelun-Todd, Deborah] US Dept Vet Affairs, Rocky Mt MIRECC, 500 Foothill Dr, Salt Lake City, UT 84148 USA; [Lyoo, In Kyoon] EwhaWomans Univ, Ewha Brain Inst, 150 Bugahyeon Ro, Seoul 03759, South Korea; [Lyoo, In Kyoon] Ewha Womans Univ, Dept Brain & Cognit Sci, 150 Bugahyeon Ro, Seoul 03759, South Korea; [Lyoo, In Kyoon] Ewha Womans Univ, Grad Sch Pharmaceut Sci, 52 Ewhayeodae Gil, Seoul 03760, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 HINDAWI LTD
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000150015
- 본문언어 영어
- Published As http://dx.doi.org/10.1155/2018/8142631
초록/요약
A number of studies have suggested that sports-related concussion (SRC) may place individuals at increased risk for depression and negative outcomes including suicide. However, the mechanisms underlying a potential relationship between brain integrity and mood remain unclear. The current study is aimed at examining the association between amygdala shape, mood state, and postconcussion symptoms in collegiate football players. Thirty members of 1 football team completed the Profile of Mood States (POMS), the postconcussion symptom scale (PCSS), and an MRI protocol during preseason camp. T1-weighted images were acquired and three-dimensional amygdala and probabilistic maps were created for shape analysis. Correlation analyses between POMS and PCSS and the relationship between POMS and amygdala shape were completed. In the amygdala, the left laterobasal subregion showed a positive relationship with the POMS total score and subscales scores. No significant relationship between PCSS and amygdala shape was found. Significant positive correlations were found between POMS subscales and PCSS. These results indicate that amygdala structure may be more closely associated with negative mood states than postconcussion symptoms. These findings suggest that premorbid individual differences in effect may provide critical insight into the relationship between negative mood and outcomes in collegiate football players with SRC.
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