Demographic and clinical features of hidradenitis suppurativa in Korea
- 주제(키워드) Asia , epidemiology , hidradenitis suppurativa , severity , treatment
- 주제(기타) Dermatology
- 설명문(일반) [Yang, Ji Hoon; Moon, Jungyoon; Suh, Dae Hun] Seoul Natl Univ, Coll Med, Dept Dermatol, Seoul, South Korea; [Kye, Young Chul; Ahn, Hyo Hyun] Korea Univ, Coll Med, Dept Dermatol, Seoul, South Korea; [Kim, Kwang Joong] Hallym Univ, Dept Dermatol, Coll Med, Anyang, South Korea; [Kim, Myeung Nam] Chung Ang Univ, Coll Med, Dept Dermatol, Seoul, South Korea; [Ro, Young Suck] Hanyang Univ, Coll Med, Dept Dermatol, Seoul, South Korea; [Park, Mi Youn] Natl Med Ctr, Dept Dermatol, Seoul, South Korea; [Lee, Mi Woo; Choi, Yu Sung] Univ Ulsan, Dept Dermatol, Coll Med, Seoul, South Korea; [Lee, Weon Ju] Kyungpook Natl Univ, Sch Med, Dept Dermatol, Daegu, South Korea; [Lee, Ju Hee] Yonsei Univ, Coll Med, Dept Dermatol, Seoul, South Korea; [Lee, Jee Bum] Chonnam Natl Univ, Med Sch, Dept Dermatol, Gwangju, South Korea; [Jang, Min Soo] Kosin Univ, Coll Med, Dept Dermatol, Busan, South Korea; [Choi, You Won] Ewha Womans Univ, Sch Med, Dept Dermatol, Seoul, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 WILEY
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000156095
- 본문언어 영어
- Published As http://dx.doi.org/10.1111/1346-8138.14656
초록/요약
Hidradenitis suppurativa (HS) is a chronic, relapsing, inflammatory skin disorder. Although several epidemiological studies have been conducted in Western countries, such data regarding Asian populations are scarce. In this study, we sought to investigate the demographic and clinical features of HS in Korea. A total of 438 patients, diagnosed with HS from May 2007 to April 2017, were enrolled and the electronic medical record of each patient was reviewed. Male patients were predominant with a male : female ratio of 2.5:1. Mean age of disease onset was 23.9 years and most patients had no family history. The most frequently affected area was the buttocks, followed by axillae and groin. Acne and diabetes mellitus were the most prevalent associated diseases and no patients with inflammatory bowel diseases were observed. In the univariable analysis, male patients had severe diseases compared with females with an odds ratio (OR) of 1.790. Two or more affected body regions were associated with HS severity with an OR of 1.693. While involvement of the perineum (OR, 4.067) and buttocks (OR, 1.471) tended to be associated with increased severity of the disease, the inguinal area (OR, 0.620) showed a tendency to be inversely associated with the severity. In multivariable analysis, identified risk factors were the involvement of the perineum (OR, 3.819) and buttocks (OR, 2.288). Smoking status and high body mass index seemed to be associated with more severe diseases. Our results will provide clinical characteristics of HS patients in Asia and help to broaden understanding of HS.
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