Factors influencing vision-related quality of life according to glaucoma severity
- 주제(키워드) glaucoma , quality of life , severity , visual acuity , visual field
- 주제(기타) Ophthalmology
- 설명문(일반) [Chun, Yeoun Sook] Chung Ang Univ, Chung Ang Univ Hosp, Coll Med, Dept Ophthalmol, Seoul, South Korea; [Sung, Kyung Rim] Univ Ulsan, Coll Med, Asan Med Ctr, Dept Ophthalmol, Seoul, South Korea; [Park, Chan Kee] Catholic Univ Korea, Coll Med, Seoul St Marys Hosp, Dept Ophthalmol, Seoul, South Korea; [Kim, Hwang Ki] Kims Eye Hosp, Seoul, South Korea; [Yoo, Chungkwon; Kim, Yong Yeon] Korea Univ, Dept Ophthalmol, Coll Med, Seoul, South Korea; [Park, Ki Ho] Seoul Natl Univ Hosp, Dept Ophthalmol, Seoul, South Korea; [Kim, Chan Yun] Yonsei Univ, Dept Ophthalmol, Coll Med, Seoul, South Korea; [Choi, Kyu-Ryong] Ewha Womans Univ, Sch Med, Dept Ophthalmol, Seoul, South Korea; [Lee, Kyoo Won] Cheil Eye Hosp, Daegu, South Korea; [Han, Seungbong] Gachon Univ, Dept Appl Stat, Seoul, South Korea; [Kim, Chang Sik] Chungnam Natl Univ Hosp, Dept Ophthalmol, Seoul, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 WILEY
- 발행년도 2019
- URI http://www.dcollection.net/handler/ewha/000000159771
- 본문언어 영어
- Published As http://dx.doi.org/10.1111/aos.13918
- PubMed https://pubmed.ncbi.nlm.nih.gov/30264446
초록/요약
Purpose To identify factors influencing vision-related quality of life (VRQOL) according to glaucoma severity. Methods A total of 901 patients with varying stages of glaucoma were recruited from the prospectively designed LIGHT (Life Quality of Glaucoma Patients Who Underwent Treatment) study organized by the Korean Glaucoma Society. Participants completed a basic questionnaire collecting socioeconomic status and clinical information, in addition to the 25-item National Eye Institute Visual Function Questionnaire (NEI VFQ-25). Subjects were classified by mean deviation (MD) of integrated binocular visual field (IVF) into mild, moderate and severe damage groups. Factors were evaluated for their influence on VRQOL according to glaucoma severity using univariate and multivariable regression models between Rasch-analysed NEI VFQ-25 subscale scores and different variables. Results The mild, moderate and severe groups contained 720, 111 and 70 patients, respectively; the mean IVF MD in each group was -1.4, -8.5 and -17.9 dB. Significant differences were observed among the three groups with respect to age, IVF MD, visual acuity (VA), education level, income level, number of glaucoma medications prescribed and follow-up period. The most influential factor associated with VRQOL according to glaucoma severity was VA. The VA of the better eye was much more influential on VRQOL than the VA of the worse eye in the moderate and severe defect groups, and the impact of VA on VRQOL was more prominent in advanced glaucoma. Conclusions Visual acuity is the most influential factor on VRQOL in patients with glaucoma. Preservation of VA should be strongly prioritized to maintain good VRQOL.
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