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Clinical Factors Associated with Adherence to the Follow-Up Examination after Positive Fecal Occult Blood Test in National Colorectal Cancer Screening

  • 주제(키워드) colorectal cancer , fecal occult blood test , follow-up examination , compliance
  • 주제(기타) Medicine, General & Internal
  • 설명문(일반) [Kim, Byung Chang] Natl Canc Ctr, Ctr Colorectal Canc, Ctr Canc Prevent & Detect, Canc Epidemiol Branch,Res Inst & Hosp, Goyang Si 10408, Gyeonggi Do, South Korea; [Kang, Minjoo; Park, Eunjung; Shim, Jeong-Im; Kang, Shinhee; Lee, Jessie; Tchoe, Ha Jin] Natl Evidence Based Healthcare Collaborating Agcy, Seoul, South Korea; [Kong, Kyeong Ae] Ewha Womans Univ, Coll Med, Dept Prevent Med, Seoul 03760, South Korea; [Kim, Duk Hwan] CHA Univ, Digest Dis Ctr, Dept Internal Med, Sch Med, Gyeonggi Do 11160, South Korea; [Kim, Yu Jin] Hallym Univ, Dept Internal Med, Coll Med, Gangwon Do 24252, South Korea; [Choi, Kui Son] Natl Canc Ctr, Grad Sch Canc Sci & Policy, Dept Canc Control & Populat Hlth, 323 Ilsan Ro, Goyang Si 10408, Gyeonggi Do, South Korea; [Moon, Chang Mo] Ewha Womans Univ, Coll Med, Dept Internal Med, 1071 Anyangcheon Ro, Seoul 07985, South Korea; [Moon, Chang Mo] Ewha Womans Univ, Tissue Injury Def Res Ctr, Seoul 03760, South Korea
  • 등재 SCIE, SCOPUS
  • OA유형 Green Published, gold
  • 발행기관 MDPI
  • 발행년도 2020
  • 총서유형 Journal
  • URI http://www.dcollection.net/handler/ewha/000000169336
  • 본문언어 영어
  • Published As https://dx.doi.org/10.3390/jcm9010260
  • PubMed https://pubmed.ncbi.nlm.nih.gov/31963658

초록/요약

Background: The compliance with the follow-up examination after a positive fecal occult blood test (FOBT) is lower than expected. We aimed to evaluate the adherence rate to the follow-up examination in patients with a positive FOBT and to identify the clinical factors associated with this adherence. Methods: The study population comprised adults aged >= 50 years who participated in the National Cancer Screening Program for colorectal cancer (CRC) in 2013. Compliance was defined as undergoing follow-up examination within 1 year of a positive FOBT. Results: From 214,131 individuals with a positive FOBT, 120,911 (56.5%) were in the compliance group and 93,220 (43.5%) were in the non-compliance group. On multivariate analysis, good compliance was associated with men (odds ratio (OR) = 1.12, 95% confidence interval (CI) (1.09-1.15)), younger ages (70-79 years, OR = 2.19 (2.09-2.31); 60-69 years, OR = 3.29 (3.13-3.46); 50-59 years, OR = 3.57 (3.39-3.75) vs. >80 years), previous experience of CRC screening (a negative FOBT, OR = 1.18 (1.15-1.21); a positive FOBT, OR = 2.42 (2.31-2.54)), absent previous experience of colonoscopy or barium enema (OR = 2.06 (1.99-2.13)), higher economic income (quartile, 75%, OR = 1.14 (1.11-1.17); 100%, OR = 1.22 (1.19-1.25)), current smokers (OR = 1.12 (1.09-1.15)), alcohol intake (OR = 1.03 (1.01-1.05)), active physical activity (>= 3 times/week, OR = 1.13 (1.11-1.15)), depression (OR = 1.11 (1.08-1.14)), and present comorbidities (Charlson Comorbidity Index, >= 1). Conclusion: This study identified clinical factors, namely, male, younger ages, prior experience of fecal test, absent history of colonoscopy or double-contrast barium enema (DCBE) within 5 years, and high socioeconomic status to be associated with good adherence to the follow-up examination after a positive FOBT.

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