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International Waist Circumference Percentile Cutoffs for Central Obesity in Children and Adolescents Aged 6 to 18 Years

  • 주제(기타) Endocrinology & Metabolism
  • 설명문(일반) [Xi, Bo] Shandong Univ, Sch Publ Hlth, Dept Epidemiol, Jinan 250012, Peoples R China; [Zong, Xin'nan] Capital Inst Pediat, Dept Growth & Dev, Beijing 10020, Peoples R China; [Kelishadi, Roya; Ardalan, Gelayol] Isfahan Univ Med Sci, Child Growth & Dev Res Ctr, Res Inst Primordial Prevent Noncommunicable Dis, Dept Pediat, Esfahan 8167636954, Iran; [Litwin, Mieczyslaw] Childrens Mem Hlth Inst, Dept Nephrol & Arterial Hypertens, PL-04730 Warsaw, Poland; [Hong, Young Mi; Kim, Hae Soon] Ewha Womans Univ, Dept Pediat, Sch Med, Seoul 07804, South Korea; [Poh, Koon; Ruzita, Abd Talib] Univ Kebangsaan Malaysia, Fac Hlth Sci, Nutr Sci Programme, Kuala Lumpur 50300, Malaysia; [Poh, Koon; Ruzita, Abd Talib] Univ Kebangsaan Malaysia, Fac Hlth Sci, Ctr Community Hlth Studies, Kuala Lumpur 50300, Malaysia; [Steffen, Lyn M.] Univ Minnesotas, Div Epidemiol & Community Hlth, Sch Publ Hlth, Minneapolis, MN 55454 USA; [Galcheva, Sonya, V; Iotova, Violeta M.] Varna Med Univ, Dept Pediat, Varna 9010, Bulgaria; [Herter-Aeberli, Isabelle] Swiss Fed Inst Technol, Human Nutr Lab, Inst Food Nutr & Hlth, CH-8092 Zurich, Switzerland; [Nawarycz, Tadeusz; Ostrowska-Nawarycz, Lidia] Med Univ Lodz, Dept Biophys, Chair Expt & Clin Physiol, PL-90136 Lodz, Poland; [Stawinska-Witoszynska, Barbara; Krzyzaniak, Alicja] Poznan Univ Med Sci, Dept Epidemiol & Hyg, Chair Social Med, PL-60806 Poznan, Poland; [Khadilkar, Anuradha; Ekbote, Veena; Khadilkar, Vaman] Jehangir Hosp, Hirabai Cowasji Jehangir Med Res Inst, Pune 411001, Maharashtra, India; [Schmidt, Michael D.] Univ Georgia, Dept Kinesiol, Athens, GA 30602 USA; [Neuhauser, Hannelore] DZHK German Ctr Cardiovasc Res, Partner Site Berlin, D-12101 Berlin, Germany; [Neuhauser, Hannelore; Schienkiewitz, Anja] Robert Koch Inst, Dept Epidemiol & Hlth Monitoring, Berlin, Germany; [Kulaga, Zbigniew; Grajda, Aneta] Childrens Mem Hlth Inst, Dept Publ Hlth, PL-04730 Warsaw, Poland; [Motlagh, Mohammad Esmaeil] Ahvaz Jundishapur Univ Med Sci, Dept Pediat, Ahwaz 6135715794, Iran; [Ismail, Mohd Noor] Taylors Univ, Fac Social Sci & Leisure Management, Subang Jaya 47500, Selangor, Malaysia; [Heshmat, Ramin] Univ Tehran Med Sci, Chron Dis Res Ctr, Endocrinol & Metab Populat Sci Inst, Dept Epidemiol, Tehran 1411713137, Iran; [Stratev, Velin] Varna Med Univ, Dept Internal Med, Varna 9010, Bulgaria; [Rozdzynska-Swiatkowska, Agnieszka; Swiader-Lesniak, Anna] Childrens Mem Hlth Inst, Dept Anthropometry, PL-04730 Warsaw, Poland; [Qorbani, Mostafa] Alborz Univ Med Sci, Noncommunicable Dis Res Ctr, Karaj 3147747779, Iran; [Yotov, Yoto] Med Univ Varna, Dept Cardiol, Varna 9010, Bulgaria; [Venn, Alison J.; Dwyer, Terence; Magnussen, Costan G.] Univ Tasmania, Menzies Inst Med Res, Hobart, Tas 7000, Australia; [Dwyer, Terence] Univ Oxford, Oxford Martin Sch, George Inst Global Hlth, Oxford OX3 9DU, England; [Dwyer, Terence] Univ Oxford, Nuffield Dept Womens & Reprod Hlth, Oxford OX3 9DU, England; [Zhao, Min] Shandong Univ, Sch Publ Hlth, Dept Nutr, Jinan 250012, Peoples R China; [Zhao, Min] Shandong Univ, Sch Publ Hlth, Dept Food Hyg, Jinan 250012, Peoples R China; [Magnussen, Costan G.] Univ Turku, Res Ctr Appl & Prevent Cardiovasc Med, Turku 20520, Finland; [Bovet, Pascal] Univ Lausanne, Ctr Primary Care & Publ Hlth Unisante, Dept Epidemiol & Hlth Serv, CH-1012 Lausanne, Switzerland
  • 등재 SCIE, SCOPUS
  • OA유형 Green Accepted, Bronze, Green Published
  • 발행기관 ENDOCRINE SOC
  • 발행년도 2020
  • 총서유형 Journal
  • URI http://www.dcollection.net/handler/ewha/000000171965
  • 본문언어 영어
  • Published As https://dx.doi.org/10.1210/clinem/dgz195
  • PubMed https://pubmed.ncbi.nlm.nih.gov/31723976

초록/요약

Context: No universal waist circumference (WC) percentile cutoffs used have been proposed for screening central obesity in children and adolescents. Objective: To develop international WC percentile cutoffs for children and adolescents with normal weight based on data from 8 countries in different global regions and to examine the relation with cardiovascular risk. Design and Setting: We used pooled data on WC in 113,453 children and adolescents (males 50.2%) aged 4 to 20 years from 8 countries in different regions (Bulgaria, China, Iran, Korea, Malaysia, Poland, Seychelles, and Switzerland). We calculated WC percentile cutoffs in samples including or excluding children with obesity, overweight, or underweight. WC percentiles were generated using the general additive model for location, scale, and shape (GAMLSS). We also estimated the predictive power of the WC 90th percentile cutoffs to predict cardiovascular risk using receiver operator characteristics curve analysis based on data from 3 countries that had available data (China, Iran, and Korea). We also examined which WC percentiles linked with WC cutoffs for central obesity in adults (at age of 18 years). Main Outcome Measure: WC measured based on recommendation by the World Health Organization. Results: We validated the performance of the age- and sex-specific 90th percentile WC cutoffs calculated in children and adolescents (6-18 years of age) with normal weight (excluding youth with obesity, overweight, or underweight) by linking the percentile with cardiovascular risk (area under the curve [AUC]: 0.69 for boys; 0.63 for girls). In addition, WC percentile among normal weight children linked relatively well with established WC cutoffs for central obesity in adults (eg, AUC in US adolescents: 0.71 for boys; 0.68 for girls). Conclusion: The international WC cutoffs developed in this study could be useful to screen central obesity in children and adolescents aged 6 to 18 years and allow direct comparison of WC distributions between populations and over time.

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