Accessory pathway-related left ventricular wall motion abnormality and the effects of radiofrequency catheter ablation in patients with Wolff-Parkinson-White syndrome
- 주제(키워드) accessory pathway , cardiomyopathy , catheter ablation , wall motion abnormality , WPW syndrome
- 주제(기타) Cardiac & Cardiovascular Systems
- 설명문(일반) [Uhm, Jae-Sun; Nam, Jong-Ho; Yu, Hee Tae; Yang, Pil-Sung; Kim, Tae-Hoon; Cho, In-Jeong; Shim, Chi Young; Joung, Boyoung; Hong, Geu-Ru; Pak, Hui-Nam; Lee, Moon-Hyoung] Yonsei Univ, Coll Med, Severance Hosp, Div Cardiol,Dept Internal Med, Seoul, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 WILEY
- 발행년도 2019
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000171968
- 본문언어 영어
- Published As https://dx.doi.org/10.1111/jce.13753
초록/요약
Introduction The objective of the current study was to elucidate the effects of the accessory pathways (APs) on the left ventricular (LV) wall motion and radiofrequency catheter ablation (RFCA) on AP-related regional wall motion abnormality (RWMA) in patients with Wolff-Parkinson-White (WPW) syndrome. Methods and Results We included 348 consecutive patients (age, 37.6 +/- 17.3 years; men, 58.3%) with WPW syndrome who underwent RFCA for AP. We analyzed electrocardiographic data, the AP location, LV ejection fraction (LVEF), and RWMA patterns and their changes after RFCA. The locations of APs were right, septal, and left in 78, 94, and 176 patients, respectively. RWMA at the AP location (44.9%, 51.1%, and 17.6%, respectively; P < 0.001), decreased LVEF (10.3%, 6.4%, and 1.1%, respectively; P = 0.004), and dyskinesia (16.7%, 16.0%, and 1.1%, respectively; P < 0.001) were significantly more frequent in patients with a right or septal AP than in those with a left AP. In 31 of 50 patients with RWMA who underwent post-RFCA echocardiography (62.0%), RWMA was completely improved after RFCA. Right AP (odds ratio [OR], 22.084; 95% confidence interval [CI], 3.628-134.420; P = 0.001) and dyskinesia (OR, 6.275; 95% CI, 1.186-33.213; P = 0.031) were significantly associated with the absence of RWMA improvement after RFCA. Conclusions AP-related RWMA is frequent in patients with right or septal APs. A substantial number of patients with right AP or dyskinesia may show no improvement in RWMA after RFCA.
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