Recurrent meningococcal meningitis with complement 6 (C6) deficiency A case report
- 주제(키워드) C6 deficiency , complement deficiency , meningococcal meningitis , Neisseria meningitidis
- 주제(기타) Medicine, General & Internal
- 설명문(일반) [Bae, Ji Yun; Ham, Ahrong; Choi, Hee Jung; Kim, Chung-Jong] Ewha Womans Univ, Sch Med, Dept Internal Med, 25,Magokdong Ro 2 Gil, Seoul 07804, South Korea
- 등재 SCIE, SCOPUS
- OA유형 gold, Green Published
- 발행기관 LIPPINCOTT WILLIAMS & WILKINS
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000172393
- 본문언어 영어
- Published As https://dx.doi.org/10.1097/MD.0000000000020362
- PubMed https://pubmed.ncbi.nlm.nih.gov/32481330
초록/요약
Rationale: Late complement deficiency increases susceptibility to meningococcal disease and recurrent infections. In Korea, 5 case reports have described meningococcal disease with complement deficiency. However, C6 deficiency has not been described previously. Patient concerns: A 21-year-old police trainee presented with recurrent meningococcal meningitis. He was housed in communal living quarters until 20 days before the initial symptom onset. Diagnosis: He was diagnosed with meningococcal meningitis with C6 deficiency. Interventions: He was treated with intravenous ceftriaxone. An additional dose of quadrivalent meningococcal conjugate vaccine was administered after discharge. Outcomes: He was discharged without complications. Lessons: Screening for complement deficiency is necessary in patients with a history of recurrent meningococcal infections to provide appropriate care and prevent recurrent infections.
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