Prenatal Exposure to Alcohol, Tobacco, and Coffee: Associated Congenital Complications and Adverse Birth Outcomes
- 주제(키워드) fetal programming , prenatal alcohol exposure , prenatal tobacco exposure , birth complications , maternal malnutrition , adverse birth outcomes
- 주제(기타) Environmental Sciences
- 주제(기타) Public, Environmental & Occupational Health
- 설명문(일반) [Oh, Sarah Soyeon; Park, Sunwha; You, Young-Ah; Jee, Yongho; Ansari, AbuZar; Kim, Soo Min; Lee, Gain; Kim, Young Ju] Ewha Womans Univ, Mokdong Hosp, Fetal Alcohol Syndrome Prevent Ctr, Ewha Inst Convergence Med, Seoul 07985, South Korea; [Oh, Sarah Soyeon; Park, Sunwha; Kim, Young Ju] Ewha Womans Univ, Coll Med, Dept Obstet & Gynecol, Seoul 07985, South Korea; [You, Young-Ah; Ansari, AbuZar; Kim, Young Ju] Ewha Womans Univ, Coll Med, Med Res Inst, Seoul Hosp, Seoul 07985, South Korea; [Jee, Yongho] Ewha Womans Univ, Adv Biomed Res Inst, Seoul Hosp, Seoul 07985, South Korea; [Kim, Soo Min; Lee, Gain; Kim, Young Ju] Ewha Womans Univ, Grad Program Syst Hlth Sci & Engn, Seoul 03760, South Korea
- 등재 SCIE, SSCI, SCOPUS
- 발행기관 MDPI
- 발행년도 2021
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000181517
- 본문언어 영어
- Published As http://dx.doi.org/10.3390/ijerph18063140
초록/요약
A few studies to date have examined the association between prenatal exposure to alcohol, tobacco, and coffee, and congenital complications/adverse birth outcomes among South Korean populations. Thus, this study analyzed the data of 1675 Korean women with birth experience within the last 3 years for pregnancy-related health and nutritional behaviors and relative outcomes. During their pregnancies, 11.58% of the study population consumed alcohol at least once, 1.43% drank throughout all three trimesters, 1.13% smoked, 25.43% were exposed to secondhand smoking, and 28.18% consumed 3 coffees or more every day. Prenatal alcohol exposure was associated with 11.24 times increased risk of birth defects/disabilities [Odds Ratio (OR): 11.24, 95% Confidence Interval (CI) 1.07-117.86] and 10.66 times increased risk of inherited metabolic diseases (OR: 10.66, 95% CI: 1.08-104.82). Prenatal secondhand smoke exposure (OR: 1.62, 95% CI: 1.01-2.62) and coffee consumption (OR: 1.92, 95% CI: 1.22-3.03) was associated with increased risk of low birth weight. Such results were in alignment with that of previous studies and confirmed that prenatal alcohol, tobacco, and coffee exposure can have detrimental neonatal and maternal consequences.
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