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Cohort profile: the Ewha Birth and Growth Study

  • 주제(키워드) Cohort studies , Child health , Cardiometabolic risk factors , Metabolic syndrome
  • 주제(기타) Public, Environmental & Occupational Health
  • 설명문(일반) [Lee, Hye Ah] Ewha Womans Univ, Clin Trial Ctr, Mokdong Hosp, Seoul, South Korea; [Park, Bohyun] Natl Canc Ctr, Natl Canc Control Inst, Goyang, South Korea; [Min, Jungwon] Childrens Hosp Philadelphia, Dept Biomed & Hlth Informat, Philadelphia, PA 19104 USA; [Choi, Eun Jeong; Kim, Ui Jeong; Park, Hyun Jin; Park, Hyesook] Ewha Womans Univ, Dept Prevent Med, Coll Med, 25 Magokdong Ro 2 Gil, Seoul 07804, South Korea; [Kim, Ui Jeong; Park, Hyun Jin; Kim, Young Ju; Ha, Eun Hee; Park, Hyesook] Ewha Womans Univ, Grad Program Syst Hlth Sci & Engn, Seoul, South Korea; [Park, Eun Ae; Cho, Su Jin; Kim, Hae Soon] Ewha Womans Univ, Dept Pediat, Coll Med, Seoul, South Korea; [Lee, Hwayoung] Ewha Womans Univ, Dept Anat, Coll Med, Seoul, South Korea; [Kim, Young Ju] Ewha Womans Univ, Dept Obstet & Gynecol, Coll Med, Seoul, South Korea; [Hong, Young Sun] Ewha Womans Univ, Dept Internal Med, Coll Med, Seoul, South Korea; [Kim, Eui-Jung] Ewha Womans Univ, Dept Psychiat, Coll Med, Seoul, South Korea; [Ha, Eun Hee] Ewha Womans Univ, Dept Occupat & Environm Med, Coll Med, Seoul, South Korea
  • 등재 SCIE, SCOPUS
  • 발행기관 KOREAN SOC EPIDEMIOLOGY
  • 발행년도 2021
  • 총서유형 Journal
  • URI http://www.dcollection.net/handler/ewha/000000181580
  • 본문언어 영어
  • Published As http://dx.doi.org/10.4178/epih.e2021016

초록/요약

With the introduction of life-course epidemiology, researchers realized the importance of identifying risk factors in early life to prevent chronic diseases. 'ibis led to the establishment of the Ewha Birth and Growth Study in 2001; the study is a prospective birth cohort designed to provide evidence of early life risk factors for a child's growth and health. Participants were recruited from those who visited Ewha Womans University Mokdong hospital (a tertiary hospital in southwest Seoul, Korea) for prenatal care at 24-28 weeks of gestation. In total, 891 mothers enrolled in this study between 2001 and 2006 and their offspring (n=940) were followed-up. Regular check-up examinations of offspring were conducted at 3 years, 5 years, and 7 years of age and every year thereafter. To consider age-related health issues, extensive data were collected using questionnaires and measurements. In 2021, the study subjects will reach 19 years of age, and we are planning a check-up examination for early adulthood. About 20 years have passed since the cohort data were collected, and we have published results on childhood health outcomes associated with prenatal and birth characteristics, genetic and epigenetic characteristics related to childhood metabolism, the effects of exposure to endocrine disruptors, and dietary patterns in childhood. Recently, we started reporting on topics related to adolescent health. The findings will facilitate identification of early life risk factors for chronic diseases and the development of interventions for diseases later in life.

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