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Clinical Course of COVID-19 in Patients with Inflammatory Bowel Disease in Korea: a KASID Multicenter Study

  • 주제(키워드) COVID-19 , Crohn's Disease , Inflammatory Bowel Disease , Ulcerative Colitis
  • 주제(기타) Medicine, General & Internal
  • 설명문(일반) [Lee, Jin Wook] Keimyung Univ, Dept Internal Med, Sch Med, Daegu, South Korea; [Lee, Jin Wook; Hong, Seung Wook; Park, Jin Hwa; Hwang, Sung Wook; Yang, Dong-Hoon; Ye, Byong Duk; Byeon, Jeong-Sik; Myung, Seung-Jae; Yang, Suk-Kyun; Park, Sang Hyoung] Univ Ulsan, Asan Med Ctr, Dept Gastroenterol, Coll Med, 88 Olymp Ro 43 Gil, Seoul 05505, South Korea; [Song, Eun Mi; Jung, Sung-Ae] Ewha Womans Univ, Coll Med, Dept Internal Med, Seoul, South Korea; [Jung, Sung Hoon] Catholic Univ Korea, Coll Med, Dept Internal Med, Eunpyeong St Marys Hosp, Seoul, South Korea; [Kim, Kwang Woo; Koh, Seong-Joon; Lee, Hyun Jung] Seoul Natl Univ, Liver Res Inst, Dept Internal Med, Coll Med, Seoul, South Korea
  • 등재 SCIE, SCOPUS, KCI등재
  • OA유형 Green Published, gold
  • 발행기관 KOREAN ACAD MEDICAL SCIENCES
  • 발행년도 2021
  • 총서유형 Journal
  • URI http://www.dcollection.net/handler/ewha/000000190760
  • 본문언어 영어
  • Published As https://doi.org/10.3346/jkms.2021.36.e336
  • PubMed https://pubmed.ncbi.nlm.nih.gov/34904410

초록/요약

In 2020, the novel coronavirus disease 2019 (COVID-19) began to spread worldwide and remains an ongoing medical challenge. This case series reports on the clinical features and characteristics of patients with inflammatory bowel disease (IBD) and confirmed COVID-19 infection. From February 2020 to March 2021, nine patients with IBD had confirmed COVID-19 across four hospitals in Korea. The median age at COVID-19 diagnosis was 42 years. Six patients were male, and seven patients had ulcerative colitis (UC). No patients required oxygen therapy, intensive care unit hospitalizations, or died. The most common symptom was fever, and gastrointestinal (GI) symptoms developed as diarrhea in five patients with UC. Oral steroids were used to combat UC aggravation in two patients. In this case series of nine IBD patients diagnosed with COVID-19 in Korea, the clinical presentation was predominately a mild respiratory tract infection. Most patients with UC developed new GI symptoms including diarrhea.

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