Standardized Rhus verniciflua Stokes Extract and Its Major Flavonoid Fustin Attenuate Oxidative Stress Induced by Tert-butyl hydroperoxide via Activation of Nuclear Factor Erythroid 2-related Factor
- 주제(키워드) fustin , glutathione , nuclear factor erythroid 2-related factor , Rhus verniciflua Stokes , tert-butyl hydroperoxide
- 등재 SCIE, KCI등재, SCOPUS
- 발행기관 KOREAN SOC APPLIED BIOLOGICAL CHEMISTRY
- 발행년도 2014
- URI http://www.dcollection.net/handler/ewha/000000090737
- 본문언어 영어
- Published As http://dx.doi.org/10.1007/s13765-013-4201-7
초록/요약
The antioxidant effects of an urushiol-free standardized Rhus verniciflua Stokes (RVS) extract and fustin were investigated using oxidative stress-induced rats by tert-butyl hydroperoxide (t-BHP). Hepatic glutathione levels were higher in RVS and fustin groups than those of the t-BHP treated control group. The level of hepatic nuclear factor erythroid 2-related factor was increased by RVS and fustin. The histology results indicated that rats fed RVS had a lower rate of necrosis than the control rats injected with t-BHP.
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