Nonenzymatic amperometric sensor for ascorbic acid based on hollow gold/ruthenium nanoshells
- 주제(키워드) Hollow gold ruthenium , Nonenzymatic ascorbic acid sensor , Electrocatalyst , Amperometric sensor , Biosensor
- 등재 SCIE, SCOPUS
- 발행기관 ELSEVIER SCIENCE BV
- 발행년도 2014
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000091314
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.aca.2014.02.017
초록/요약
We report a new nonenzymatic amperometric detection of ascorbic acid (AA) using a glassy carbon (GC) disk electrode modified with hollow gold/ruthenium (hAu-Ru) nanoshells, which exhibited decent sensing characteristics. The hAu-Ru nanoshells were prepared by the incorporation of Ru on hollow gold (hAu) nanoshells from Co nanoparticle templates, which enabled AA selectivity against glucose without aid of enzyme or membrane. The structure and electrocatalytic activities of the hAu-Ru catalysts were characterized by spectroscopic and electrochemical techniques. The hAu-Ru loaded on GC electrode (hAu-Ru/GC) showed sensitivity of 426 mu A mM(-1) cm(-2) (normalized to the GC disk area) for the linear dynamic range of <5 mu M to 2 mM AA at physiological pH. The response time and detection limit were 1.6 s and 2.2 mu M, respectively. Furthermore, the hAu-Ru/GC electrode displayed remarkable selectivity for ascorbic acid over all potential biological interferents, including glucose, uric acid (UA), dopamine (DA), 4-acetamidophenol (AP), and nicotinamide adenine dinucleotide (NADH), which could be especially good for biological sensing. (C) 2014 Elsevier B.V. All rights reserved.
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