Robust ZnO nanoparticle embedded memory device using vancomycin conjugate and its biorecognition for electrical charging node
- 주제(키워드) ZnO nanoparticles , Vancomycin , Self-assembly monolayer , Memory device , Biorecognition , Bioelectronics
- 등재 SCIE, SCOPUS
- 발행기관 ELSEVIER ADVANCED TECHNOLOGY
- 발행년도 2014
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000091347
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.bios.2013.12.049
초록/요약
Conjugation of antibiotic vancomycin (VAN) on nanoparticles (NPs) has recently initiated novel works in the nanobiotechnology field. In this study, a bioelectronic structure using VAN conjugated zinc oxide (ZnO) NPs as charge storing elements on metal-pentacene-insulator-silicon (MPIS) device is demonstrated. Highly specific molecular recognition between the VAN and membrane protein unit mimicked from VAN-resistant bacteria is employed as the formation mechanism of self-assembly monolayers (SAMs) of ZnO NPs. The insulator surface is modified with the VAN cognate peptide of L-Ala-o-Glu-L-Lys-D-Ala-D-Ala by chemical activator coupling. Hysteretic behaviors in capacitance versus voltage (C-V) curves are obtained for the charged ZnO NPs exhibiting flatband voltage shifts, which demonstrate the charge storage on the VAN conjugated ZnO NPs. The potential perspective of this study will be a tangible progress of biomolecular electronics implemented by the interface between biomolecules and electronics. (C) 2013 Elsevier B.V. All rights reserved.
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