Formation of Four Different Aromatic Scaffolds from Nitriles through Tandem Divergent Catalysis
- 주제(키워드) aromatics , divergency , nitriles , palladium , tandem reactions
- 등재 SCIE, SCOPUS
- 발행기관 WILEY-V C H VERLAG GMBH
- 발행년도 2014
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000091639
- 본문언어 영어
- Published As http://dx.doi.org/10.1002/anie.201403698
초록/요약
A zinc bromide complex, formed by the sequential reaction of nitriles with a Reformatsky reagent and terminal alkynes, is used as an intermediate for divergent palladium-catalyzed reactions. The reaction pathway of the intermediate is precisely controlled by the choice of the reaction solvent or the palladium catalyst to quickly form four different aromatic scaffolds-arylamines, aminoindenes, pyrroles, and quinolines-starting from readily available nitriles.
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