Controlling mechanical properties of bio-inspired hydrogels by modulating nano-scale, inter-polymeric junctions
- 주제(키워드) catechols , hydrogels , poly(ethylene glycol)s , quinone tanning
- 등재 SCIE, SCOPUS
- 발행기관 BEILSTEIN-INSTITUT
- 발행년도 2014
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000091693
- 본문언어 영어
- Published As http://dx.doi.org/10.3762/bjnano.5.101
초록/요약
Quinone tanning is a well-characterized biochemical process found in invertebrates, which produce diverse materials from extremely hard tissues to soft water-resistant adhesives. Herein, we report new types of catecholamine PEG derivatives, PEG-NH-catechols that can utilize an expanded spectrum of catecholamine chemistry. The PEGs enable simultaneous participation of amine and catechol in quinone tanning crosslinking. The intermolecular reaction between PEG-NH-catechols forms a dramatic nano-scale junction resulting in enhancement of gelation kinetics and mechanical properties of PEG hydrogels compared to results obtained by using PEGs in the absence of amine groups. Therefore, the study provides new insight into designing new crosslinking chemistry for controlling nano-scale chemical reactions that can broaden unique properties of bulk hydrogels.
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