Phorbaketals L-N, cytotoxic sesterterpenoids isolated from the marine sponge of the genus Phorbas
- 주제(키워드) Phorbas sp. , Phorbaketals , Cytotoxicity
- 등재 SCIE, SCOPUS
- 발행기관 PERGAMON-ELSEVIER SCIENCE LTD
- 발행년도 2014
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000108818
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.bmcl.2014.07.066
초록/요약
Three new sesterterpenoids, phorbaketals L-N (1-3), were isolated from a marine sponge of the genus Phorbas and their complete structures were elucidated via analysis of HRFABMS and NMR spectroscopic data. Phorbaketal N (3) showed potent cytotoxicity against human pancreas cancer cells (IC50 = 11.4 mu M). (C) 2014 Elsevier Ltd. All rights reserved.
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