Copper-catalyzed N-arylation of tert-butyl N-sulfonylcarbamates with diaryliodonium salts at room temperature
- 주제(키워드) Copper catalysis , tert-Butyl N-sulfonylcarbamates , Diaryliodonium salts , Room temperature , Mono N-arylsulfonamides
- 등재 SCIE, SCOPUS
- 발행기관 PERGAMON-ELSEVIER SCIENCE LTD
- 발행년도 2015
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000115004
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.tet.2015.01.032
초록/요약
A new and mild synthetic approach for the synthesis of N-arylsulfonamides under copper-catalyzed conditions at room temperature has been developed. The reaction employs various tert-butyl N-sulfonylcarbamates and diaryliodonium salts to avoid potential genotoxic impurities. A one-pot coupling/Boc-deprotection sequence is also reported to provide mono N-arylsulfonamides in good to excellent yields. (C) 2015 Elsevier Ltd. All rights reserved.
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