Actinobenzoquinoline and Actinophenanthrolines A-C, Unprecedented Alkaloids from a Marine Actinobacterium
- 등재 SCIE, SCOPUS
- 발행기관 American Chemical Society
- 발행년도 2015
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000118273
- 본문언어 영어
- Published As http://dx.doi.org/10.1021/acs.orglett.5b01387
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
(Chemical Equation Presented) Chemical investigation of a marine actinomycete within the family Streptomycetaceae (our strain CNQ-149) has led to the isolation of the unprecedented alkaloids, actinobenzoquinoline (1) and actinophenanthrolines A-C (2-4). The chemical structures of 1-4 were assigned by interpretation of NMR spectroscopic data, and their absolute configurations were assigned by X-ray analysis. Actinobenzoquinoline possesses a 5-methyloxazolidin-4-one moiety and a dihydrobenzo[h]quinoline core structure, while actinophenanthrolines A-C are composed of hydroxypropanamide-substituted 1,7-phenanthroline core skeletons. © 2015 American Chemical Society.
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