Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages
- 주제(키워드) Flavonostilbenes , Nitric oxide production inhibitor , Sophora alopecuroides L.
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier Ltd
- 발행년도 2015
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000118306
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.bmcl.2015.05.062
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Abstract Three new flavonostilbenes, alopecurones M-O (1-3), were isolated from the root bark of Sophora alopecuroides L. together with 21 known compounds. The structures of the isolated compounds were elucidated by using NMR, MS, and CD spectroscopic data. All isolates were evaluated for their potential to inhibit LPS-induced nitric oxide production in RAW 264.7 cells. © 2015 Elsevier Ltd.
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