Synthesis of ketones via organolithium addition to acid chlorides using continuous flow chemistry
- 등재 SCIE, SCOPUS
- 발행기관 Royal Society of Chemistry
- 발행년도 2015
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000119555
- 본문언어 영어
- Published As http://dx.doi.org/10.1039/c5ra14890a
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
An efficient method for the synthesis of ketones using organolithium and acid chlorides under continuous flow conditions has been developed. In contrast to standard batch chemistry, over-addition of the organolithium to the ketone for the formation of the undesired tertiary alcohol has been minimised representing a direct approach toward ketones. This journal is © The Royal Society of Chemistry 2015.
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