Efficient singlet oxygen generation from sugar pendant C60 derivatives for photodynamic therapy
- 등재 SCIE, SCOPUS
- 발행기관 Royal Society of Chemistry
- 발행년도 2015
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000120479
- 본문언어 영어
- Published As http://dx.doi.org/10.1039/c5cc07353g
초록/요약
The amidation reaction between C60 with an activated ester group (1) and acetylated Glc (AcGlc) with an amino group (2) was performed to yield the target AcGlc-pendant C60 compound (3). The water soluble deacetylated compound, Glc-pendant C60 compound (4), exhibited high photocytotoxicity against HeLa cells due to the more efficient singlet oxygen generation as compared with that of Glc-pendant azafulleroids. © The Royal Society of Chemistry 2015.
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