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Infliximab as the First Retreatment in Patients with Kawasaki Disease Resistant to Initial Intravenous Immunoglobulin

초록/요약

Forty-three patients with Kawasaki disease (KD) who were resistant to initial intravenous immunoglobulin (IVIG) were randomized to receive either a second dose of IVIG (n=32) or infliximab (n=11). With IVIG retreatment 21 patients (65.6%) responded, and with infliximab 10 patients (90.9%) responded. The infliximab group had shorter duration of fever and fewer days of hospitalization. Coronary artery outcomes and adverse events were similar. Copyright © 2015 Wolters Kluwer Health, Inc. All rights reserved.

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