Two new Scalaranes from a Korean marine sponge Spongia sp
- 주제(키워드) Korean sponge , Marine natural product , Scalarane , Sesterpenoid , Spongia sp
- 등재 KCI등재, SCOPUS
- 발행기관 Korean Society of Pharmacognosy
- 발행년도 2015
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000124247
- 본문언어 영어
- Published As http://dx.doi.org/10.20307/nps.2015.21.4.289
초록/요약
Intensive chemical investigation of Korean marine sponge Spongia sp. has led to the isolation of two new scalaranes. The planar structures of the new compounds 1 and 2 were determined through 1D and 2D NMR spectral data analysis, while the relative stereochemistry of the compounds was determined based on the analysis of 1H-1H coupling constants and NOESY spectroscopic data. Compounds 1 and 2 did not display any significant biological activities on farnesoid X-activated receptor (FXR) in co-transfection assay. © 2015, Korean Society of Pharmacognosy. All rights reserved.
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