Oligonucleotide-based biosensors for in vitro diagnostics and environmental hazard detection
- 주제(키워드) Biosensors , Environmental harzard detection , In vitro diagnosis , Oligonucelotide
- 등재 SCIE, SCOPUS
- 발행기관 Springer Verlag
- 발행년도 2016
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000126580
- 본문언어 영어
- Published As http://dx.doi.org/10.1007/s00216-015-9212-2
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Oligonucleotide-based biosensors have drawn much attention because of their broad applications in in vitro diagnostics and environmental hazard detection. They are particularly of interest to many researchers because of their high specificity as well as excellent sensitivity. Recently, oligonucleotide-based biosensors have been used to achieve not only genetic detection of targets but also the detection of small molecules, peptides, and proteins. This has further broadened the applications of these sensors in the medical and health care industry. In this review, we highlight various examples of oligonucleotide-based biosensors for the detection of diseases, drugs, and environmentally hazardous chemicals. Each example is provided with detailed schematics of the detection mechanism in addition to the supporting experimental results. Furthermore, future perspectives and new challenges in oligonucleotide-based biosensors are discussed. © 2016 Springer-Verlag Berlin Heidelberg
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