An AIE and ESIPT based kinetically resolved fluorescent probe for biothiols
- 등재 SCIE, SCOPUS
- 발행기관 Royal Society of Chemistry
- 발행년도 2016
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000136218
- 본문언어 영어
- Published As http://dx.doi.org/10.1039/c5tc03272e
초록/요약
A new aggregation-induced emission and excited-state intramolecular proton transfer based fluorescent probe, containing a salicylaldazine moiety as a platform, displayed an excellent light-up ratio and a large Stokes shift for the detection of biothiols (cysteine, homocysteine, and glutathione). The salicylaldazine based fluorescent probe showed high selectivity, and sensitivity for biothiols. With the aid of different reactivities, a kinetically resolved method was successfully applied to distinguish different biothiols both in solution and cells. © The Royal Society of Chemistry 2016.
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