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Boronate based fluorescence (ESIPT) probe for peroxynitrite

초록/요약

A simple probe for the detection of peroxynitrite was developed incorporating a benzyl boronic ester "protecting'' unit. The "protecting'' unit of the probe is removed by peroxynitrite to "turn-on'' ESIPT fluorescence (4.5 fold enhancement). Furthermore, the probe was cell permeable and was used in cell imaging experiments showing an off-on response towards peroxynitrite, in HeLa and RAW 264.7 cells.

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