Activatable Photosensitizers: Agents for Selective Photodynamic Therapy
- 주제(키워드) imaging , photochemistry , photodynamic therapy , photosensitizers , singlet oxygen
- 등재 SCIE, SCOPUS
- 발행기관 Wiley-VCH Verlag
- 발행년도 2017
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000141689
- 본문언어 영어
- Published As http://dx.doi.org/10.1002/adfm.201604053
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Recent developments in the design of bifunctional and activatable photosensitizers rejuvenate the aging field of photodynamic sensitization and photodynamic therapy. While systematic studies have uncovered new dyes that can serve as potential photosensitizers, the most promising results have come from studies aimed at gaining precise control over the location and rate of cytotoxic singlet oxygen generation. As a consequence, higher selectivities and efficiencies in photodynamic treatment protocols are now within reach. This feature article highlights the variety of approaches that have been pursued to improve photodynamic therapy and to transform simple photosensitizers into smarter theranostic agents. © 2016 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim
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