4Z- and 4E-12-deoxydihydrokromycins, two naturally occurring kromycin aglycones of pikromycin from Streptomyces sp.
- 주제(키워드) 14-Membered macrolide , Kromycin derivative , Marine-derived Streptomyces sp. , Pikromycin aglycone
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier Ltd
- 발행년도 2017
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000145614
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.tetlet.2017.03.088
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
HPLC–UV guided isolation for the culture broth extract of the marine-derived bacterium Streptomyces sp. has led to the two 14-membered macrolides, 4Z- (1) and 4E-12-dehydroxykromycins (2). The chemical structures of compounds 1 and 2 were elucidated by spectral data, while the absolute stereochemistry of 1 and 2 were determined by application of circular dichroism (CD) and analysis of X-ray crystallographic data. © 2017
more