An ESIPT based fluorescence probe for ratiometric monitoring of nitric oxide
- 주제(키워드) Benzo[c]cinnoline , Cell imaging , ESIPT , Fluorescence probe , Nitric oxide (NO) , Ratiometric probe
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier B.V.
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000149586
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.snb.2017.12.073
- 저작권 이화여자대학교 논문은 저작권에 의해 보호받습니다.
초록/요약
Development of simple and selective fluorescence probes for the detection of nitric oxide (NO) is of great important because of the key roles this gasotransmitter plays in various physiological and pathological processes. Although a large number of fluorescence probes for NO have been developed thus far, only a few display ratiometric fluorescence changes. In this study, an excited-state intramolecular proton transfer (ESIPT) fluorophore based, ratiometric fluorescence probe for NO was developed. The probe shows good selectivity and sensitivity for NO over other relevant analytes. Furthermore, the probe was applied to imaging NO in living cells. © 2017 Elsevier B.V.
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