-hydroxyundec-9-enoic acid induces apoptosis by ROS mediated JNK and P38 phosphorylation in breast cancer cell lines
- 주제(키워드) anti-cancer effect , apoptosis , JNK pathway , p38 pathway , ROS , -Hydroxyundec-9-enoic acid
- 주제(기타) Biochemistry & Molecular Biology; Cell Biology
- 설명문(일반) [Ahn, Joungjwa] Jungwon Univ, Dept Food Sci & Technol, Goesan Gun, Chungbuk, South Korea; [Chung, Youn Wook] Yonsei Univ, Yonsei Cardiovasc Res Inst, Coll Med, Seoul, South Korea; [Park, Jin-Byung] Ewha Womans Univ, Dept Food Sci & Engn, Seoul, South Korea; [Yang, Kyung Mi] Yonsei Univ, Dept Biochem & Mol Biol, Coll Med, Seoul, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 WILEY
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000150078
- 본문언어 영어
- Published As http://dx.doi.org/10.1002/jcb.26267
초록/요약
-Hydroxyundec-9-enoic acid (-HUA), a plant secondary metabolite, exhibits anti-fungal activity. However, its effect on breast cancer cells is unknown. Here, we investigated the anti- breast cancer activity of -HUA and its underlying mechanism. Treatment o
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