Correlation between gut microbiota and personality in adults: A cross-sectional study
- 주제(키워드) Personality , Gut microbiota , Brain-gut axis , Neuroticism , Conscientiousness
- 주제(기타) Immunology; Neurosciences
- 설명문(일반) [Kim, Han-Na; Yun, Yeojun; Kim, Hyung-Lae] Ewha Womans Univ, Sch Med, Dept Biochem, 1071 Anyangcheon Ro, Seoul 07985, South Korea; [Ryu, Seungho; Chang, Yoosoo; Kwon, Min-Jung; Cho, Juhee; Shin, Hocheol] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Total Healthcare Ctr, Ctr Cohort Studies,Sch Med, Seoul, South Korea; [Ryu, Seungho; Chang, Yoosoo] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Dept Occupat & Environm Med, Seoul, South Korea; [Kwon, Min-Jung] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Dept Lab Med, Seoul, South Korea; [Cho, Juhee] Sungkyunkwan Univ, Dept Clin Res Design & Evaluat, SAHIST, Seoul 06351, South Korea; [Shin, Hocheol] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Sch Med, Dept Family Med, Seoul, South Korea; [Shin, Hocheol] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Hlth Screening Ctr, Sch Med, Seoul, South Korea; [Cho, Juhee] Johns Hopkins Bloomberg, Sch Publ Hlth, Dept Hlth Behav & Soc & Epidemiol, Baltimore, MD USA
- 등재 SCIE, SCOPUS
- 발행기관 ACADEMIC PRESS INC ELSEVIER SCIENCE
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000151414
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.bbi.2017.12.012
초록/요약
Personality affects fundamental behavior patterns and has been related with health outcomes and mental disorders. Recent evidence has emerged supporting a relationship between the microbiota and behavior, referred to as brain-gut relationships. Here, we first report correlations between personality traits and gut microbiota. This research was performed using the Revised NEO Personality Inventory and the sequencing data of the 16S rRNA gene in 672 adults. The diversity and the composition of the human gut micro biota exhibited significant difference when stratified by personality traits. We found that personality traits were significantly correlated with diversity of gut microbiota, while their differences were extremely subtle. High neuroticism and low conscientiousness groups were correlated with high abundance of Gammaproteobacteria and Proteobacteria, respectively when covariates, including age, sex, BMI and nutrient intake, were controlled. Additionally, high conscientiousness group also showed increased abundance of some universal butyrate-producing bacteria including Lachnospiraceae. This study was of observational and cross-sectional design and our findings must be further validated through metagenomic or metatranscriptomic methodologies, or metabolomics-based analyses. Our findings will contribute to elucidating potential links between the gut microbiota and personality, and provide useful insights toward developing and testing personality- and microbiota-based interventions for promoting health. (C) 2017 The Authors. Published by Elsevier Inc.
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