Bile duct segmental resection versus pancreatoduodenectomy for middle and distal common bile duct cancer
- 주제(키워드) Cholangiocarcinoma , Common bile duct neoplasms , Pancreaticoduodenectomy , Recurrence , Survival
- 주제(기타) Surgery
- 설명문(일반) [Kim, Naru; Lee, Huisong; Min, Seog Ki; Lee, Hyeon Kook] Ewha Womans Univ, Mokdong Hosp, Dept Surg, Sch Med, 1071 Anyangcheon Ro, Seoul 07985, South Korea
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 KOREAN SURGICAL SOCIETY
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000151540
- 본문언어 영어
- Published As http://dx.doi.org/10.4174/astr.2018.94.5.240
초록/요약
Purpose: To compare survival outcomes between bile duct segmental resection (BDR) and pancreatoduodenectomy (PD) for the treatment of middle and distal bile duct cancer. Methods: From 1997 to 2013, a total of 96 patients who underwent curative intent surgery for middle and distal bile duct cancer were identified. The patients were divided into 2 groups based on the type of operation; 20 patients were included in the BDR group and 76 patients were in the PD group. We retrospectively reviewed the clinical outcomes. Results: The number of lymph nodes (LNs) was significantly greater in patients within the PD group compared to the BDR group. The total number of LNs was 6.5 +/- 8.2 vs. 11.2 +/- 8.2 (P = 0.017) and the number of metastatic LNs was 0.4 +/- 0.9 vs. 1.0 +/- 1.5 (P = 0.021), respectively. After a median follow-up period of 24 months (range, 4-169 months), the recurrence-free survival of the PD group was superior to that of the BDR group (P = 0.035). In the patients with LN metastases, the patients undergoing PD had significantly better survival than the BDR group (P < 0.001). Conclusion: Surgeons should be cautious in deciding to perform BDR for middle and distal common bile duct cancer. PD is recommended if LN metastases are suspected.
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