Anti-Obesity Effect of Red Radish Coral Sprout Extract by Inhibited Triglyceride Accumulation in a Microbial Evaluation System and in High-Fat Diet-Induced Obese Mice
- 주제(키워드) Rhodosporidium toruloides , red radish coral sprout , triglyceride , anti-obesity
- 주제(기타) Biotechnology & Applied Microbiology; Microbiology
- 설명문(일반) [Lee, Nam Keun] Chonbuk Natl Univ, Dept Oriental Med Resources, Iksan 54596, South Korea; [Cheon, Chun Jin] Aenong Assoc, Jinan 55441, South Korea; [Rhee, Jin-Kyu] Ewha Womans Univ, Dept Food Sci & Engn, Seoul 03760, South Korea
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 KOREAN SOC MICROBIOLOGY & BIOTECHNOLOGY
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000151812
- 본문언어 영어
- Published As http://dx.doi.org/10.4014/jmb.1802.02005
초록/요약
Rhodosporidium toruloides, an oleaginous yeast, can be used as a fast and reliable evaluation tool to screen new natural lipid-lowering agents. Herein, we showed that triglyceride (TG) accumulation was inhibited by 42.6% in 0.1% red radish coral sprout extract (RRSE)-treated R. toruloides. We also evaluated the anti-obesity effect of the RRSE in a mouse model. The body weight gain of mice fed a high-fat diet (HFD) with 0.1% RRSE (HFD-RRSE) was significantly decreased by 60% compared with that mice fed the HFD alone after the 8-week experimental period. Body fat of the HFD-RRSE-fed group was dramatically reduced by 38.3% compared with that of the HFD-fed group.
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