Trends in incidence and survival of esophageal cancer in Korea: Analysis of the Korea Central Cancer Registry Database
- 주제(키워드) cancer incidence , cancer registry , esophageal cancer , survival rates
- 주제(기타) Gastroenterology & Hepatology
- 설명문(일반) [Shin, Aesun; Choe, Sunho] Seoul Natl Univ, Coll Med, Dept Prevent Med, Seoul, South Korea; [Shin, Aesun] Seoul Natl Univ, Coll Med, Canc Res Inst, Seoul, South Korea; [Jung, Hye-Kyung; Lee, Jihyun] Ewha Womans Univ, Coll Med, Dept Internal Med, 1071 Anyangcheon Ro, Seoul 07985, South Korea; [Oh, Chang-Mo] Kyung Hee Univ, Coll Med, Dept Prevent Med, Seoul, South Korea; [Won, Young-Joo; Kong, Hyun-Joo; Jung, Kyu-Won; Oh, Chang-Mo] Natl Canc Ctr, Canc Registrat & Stat Branch, Goyang, Gyeonggi Do, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 WILEY
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000155943
- 본문언어 영어
- Published As http://dx.doi.org/10.1111/jgh.14289
초록/요약
Background and Aim The diagnostic and therapeutic modalities of esophageal cancer have recently improved in Asia, and its prognosis is expected to change. This study provides a population-based report on the epidemiology of esophageal cancer in Korea. Methods Cancer incidence data from 1999 to 2013 were obtained from the Korea Central Cancer Registry, covering the entire population. Age-standardized incidence rates and annual percent changes were calculated according to subsites and histological types. Five-year relative survival rates were estimated for cases diagnosed between 1993 and 2013. Relative excess rates were compared between patients diagnosed from 2009 to 2013 and 2006 to 2008. Results The age-standardized incidence rates decreased from 8.8 per 100 000 populations in 1999 to 5.9 in 2013 with an annual percent change of -2.6% in men and -2.2% in women. The most common histological type was squamous cell carcinoma, accounting for 90.2% of all esophageal cancers in 2013, followed by adenocarcinomas (3.1%), and their incidences decreased. The proportion of localized and regional cancer tended to increase compared with that of distant cancer. Five-year relative survival of squamous cell carcinoma improved from 12.1% (1993-1995) to 34.6% (2009-2013). Relative excess rate was 0.72 (95% confidence interval 0.65-0.80) in localized stage and 0.88 (95% confidence interval, 0.82-0.95) in regional stage comparing patients diagnosed from 2009 to 2013 and 2006 to 2008. Conclusions The incidence of esophageal cancer has decreased in Korea for the past 15 years, and 5-year survival rates have improved significantly. These increases may be attributable to more effective detection of early-stage disease.
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