Antimicrobial activity of a conjugated polymer with cationic backbone
- 주제(키워드) Antimicrobial , Cationic backbone , Conjugated polymer , Imidazolium
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier Ltd
- 발행년도 2019
- URI http://www.dcollection.net/handler/ewha/000000155988
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.dyepig.2018.08.049
초록/요약
Owing to the misuse of antibiotics and slow development of new drugs, antibiotic-resistant pathogens have become a serious threat to human health. With the aim of developing new antimicrobial agents, we designed and synthesized a new conjugated polymer (PFPhim), which possesses an imidazolium containing backbone. The cationic backbone enables it to strongly interact with bacterial membrane leading to an antimicrobial ability that is more potent than that of a conjugated polymer containing a neutral backbone. PFPhim also displays strong photodynamic antimicrobial activity. © 2018 Elsevier Ltd
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