Cost-utility analysis of the National Health Screening Program for chronic kidney disease in Korea
- 주제(키워드) chronic kidney disease , cost-effectiveness , cost-utility analysis , screening
- 등재 SCIE, SCOPUS
- 발행기관 Blackwell Publishing
- 발행년도 2019
- URI http://www.dcollection.net/handler/ewha/000000156189
- 본문언어 영어
- Published As http://dx.doi.org/10.1111/nep.13203
- PubMed https://pubmed.ncbi.nlm.nih.gov/29206319
초록/요약
Aim: Although a National Health Screening Program (NHSP) for chronic kidney disease (CKD) has been implemented in Korea since 2002, its cost-effectiveness has never been determined. This study aimed to estimate the cost-utility of NHSP for CKD in Korea. Methods: A Markov decision analytic model was constructed to compare CKD screening strategies of the NHSP with no screening. We developed a model that simulated disease progression in a cohort aged 20–120 years or death from the societal perspective. Results: Biannual screening starting at age 40 for CKD by proteinuria (dipstick) and estimated glomerular filtration ratio had an ICUR of $66 874/QALY relative to no screening. The targeted screening strategy had an ICUR of $37 812/QALY and $40 787/QALY for persons with diabetes and hypertension, respectively. ICURs improved with lower cost strategies. The most influential parameter that might make screening more cost-effective was the effectiveness of treatment on CKD to decrease disease progression and mortality. Conclusions: The Korean NHSP for CKD is more cost-effective for patients with diabetes or hypertension than the general population, consistent with prior studies. Although it is too early to conclude the cost-effectiveness of the Korean NHSP for CKD, this study provides evidence that is useful in evaluating the cost-effectiveness of CKD interventions. © 2017 Asian Pacific Society of Nephrology
more