Antibody Phage Display
- 주제(키워드) Phage display , Antibody library , scFv , Fab , Bacteriophage , Synthetic antibody library , Natural antibody library , Immune antibody library
- 주제(기타) Immunology; Infectious Diseases; Medicine, Research & Experimental
- 설명문(일반) [Shim, Hyunbo] Ewha Womans Univ, Dept Bioinspired Sci, Seoul, South Korea; [Shim, Hyunbo] Ewha Womans Univ, Dept Life Sci, Seoul, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 SPRINGER INTERNATIONAL PUBLISHING AG
- 발행년도 2017
- URI http://www.dcollection.net/handler/ewha/000000156239
- ISBN 978-3-319-72077-7; 978-3-319-72076-0
- 본문언어 영어
- Published As http://dx.doi.org/10.1007/978-3-319-72077-7_2
초록/요약
Antibody phage display has become an indispensable tool for the discovery and optimization of target-specific monoclonal antibodies suitable for demanding applications including therapeutic reagents. The in vitro nature of the technology enables the rapid and efficient identification of specific binders, as well as greater control over selection parameters that facilitates the isolation of antibodies with unique, desirable functional characteristics. In this chapter, the technological background and the state of the art in the field of antibody phage display is discussed.
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