Enhancing the Performance of Surface Plasmon Resonance Biosensor via Modulation of Electron Density at the Graphene-Gold Interface
- 주제(키워드) graphene-metal interface , optical sensing , surface dipole , surface plasmon resonance
- 주제(기타) Chemistry, Multidisciplinary; Materials Science, Multidisciplinary
- 설명문(일반) [Chung, Kyungwha; Lee, June Sang; Kim, Dong Ha] Ewha Womans Univ, Dept Chem & Nano Sci, Seoul 03760, South Korea; [Kim, Eunah; Kim, Dong-Wook] Ewha Womans Univ, Dept Phys, Seoul 03760, South Korea; [Lee, Kyung-Eun; Kim, Sang Ouk] Korea Adv Inst Sci & Technol, Natl Creat Res Initiat Ctr Multidimens Directed N, Dept Mat Sci & Engn, Daejeon 34141, South Korea; [Kim, Kiheung; Kim, Donghyun] Yonsei Univ, Sch Elect & Elect Engn, Seoul 03722, South Korea; [Lee, Junghyun; Park, Hyesung] Ulsan Natl Inst Sci & Technol, Dept Energy Engn, Sch Energy & Chem Engn, Low Dimens Carbon Mat Ctr,Perovtron Res Ctr, Ulsan 44919, South Korea; [Jeon, Seokwoo] Korea Adv Inst Sci & Technol, Dept Mat Sci & Engn, Daejeon 34141, South Korea; [Kim, Dong Ha] Fudan Univ, State Key Lab Mol Engn Polymers, Collaborat Innovat Ctr Polymers & Polymer Composi, Dept Macromol Sci, Shanghai 200433, Peoples R China
- 등재 SCIE, SCOPUS
- 발행기관 WILEY
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000156290
- 본문언어 영어
- Published As http://dx.doi.org/10.1002/admi.201800433
초록/요약
Surface plasmons at a metal/dielectric interface resonate with incident light, generating an evanescent field at the interface, which is highly sensitive to the change in refractive index of the medium. These characteristics are utilized as the basis for surface plasmon resonance-based sensors with Kretschmann configuration, providing label-free and real-time monitoring of binding interaction between probe and target moieties. Although graphene is recently extensively investigated in the field of optical sensors for the improvement of sensing performance, the proposed enhancement mechanisms in each study are ambiguous and inconsistent. Here, graphene-deposited Au film as advanced plasmonic sensing substrates is reported. Work function measurements of Au-graphene with different number of layer and doping state explicitly corroborate the mechanism of sensitivity increase, confirming that the enhanced refractive index sensitivity originates from induced surface dipole due to the charge transfer between Au film and graphene. The best sensitivity is attained from two layers of graphene by a chemical vapor deposition method. Biotinylated bovine serum albumin and streptavidin are used to evaluate the biosensing performance.
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