Stress Is Associated with Poor Outcome of Acute Treatment for Chronic Migraine: A Multicenter Study
- 주제(키워드) Migraine , Chronic Migraine , Psychological Stress , Treatment Outcome , Quality of Life , Headache Disorders
- 주제(기타) Anesthesiology; Medicine, General & Internal
- 설명문(일반) [Cha, Myoung-Jin] Natl Police Hosp, Dept Neurol, Seoul, South Korea; [Kim, Byung-Kun] Eulji Univ, Eulji Hosp, Dept Neurol, Seoul, South Korea; [Moon, Heui-Soo] Sungkyunkwan Univ, Kangbuk Samsung Hosp, Dept Neurol, Sch Med, Seoul, South Korea; [Ahn, Jin-Young] Seoul Med Ctr, Dept Neurol, Seoul, South Korea; [Oh, Kyungmi] Korea Univ, Sch Med, Dept Neurol, Guro Hosp, Seoul, South Korea; [Kim, Jee Young] Seonam Univ Coll Med, Myongji Hosp, Dept Neurol, Coll Med, Goyang, South Korea; [Kim, Byung-Su] Bundang Jesaeng Gen Hosp, Daejin Med Ctr, Dept Neurol, Seongnam, South Korea; [Sohn, Jong-Hee] Hallym Univ, Chuncheon Sacred Heart Hosp, Dept Neurol, Coll Med, Chunchon, South Korea; [Chung, Jae-Myun] Inje Univ, Dept Neurol, Seoul Paik Hosp, Seoul, South Korea; [Song, Tae-Jin] Ewha Womans Univ, Coll Med, Dept Neurol, Seoul, South Korea; [Kim, Jiyoung] Pusan Natl Univ, Pusan Natl Univ Hosp, Bio Med Res Inst, Dept Neurol,Sch Med, Busan, South Korea; [Seo, Jong-Geun] Kyungpook Natl Univ, Sch Med, Dept Neurol, Daegu, South Korea; [Chu, Min Kyung] Hallym Univ, Kangnam Sacred Heart Hosp, Dept Neurol, Coll Med, 1 Singil Ro, Seoul 07441, South Korea; [Cho, Soo-Jin] Hallym Univ, Dongtan Sacred Heart Hosp, Dept Neurol, Coll Med, Keun Jae Bong Gil 7, Hwaseong 18450, Gyeonggi Do, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 OXFORD UNIV PRESS
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000156883
- 본문언어 영어
- Published As http://dx.doi.org/10.1093/pm/pnx269
초록/요약
Background. Chronic migraine (CM) is associated with severe psychological symptoms and disabilities. Information on the relationship between stress and the outcomes of acute CM treatment is limited. Methods. We evaluated the clinical presentation and stress levels of patients with CM who visited the neurology departments of 14 hospitals between September and December 2015. The patients were divided into stress and reference groups on the basis of the Korean version of the Brief Encounter Psychosocial Instrument (BEPSI-K). Quality of life was evaluated using EuroQol Five Dimension Questionnaire Three-Level. The Migraine Assessment of Current Therapy questionnaire was used to assess the outcomes of acute treatment. Results. This study included 186 CM patients. On the basis of the BEPSI-K score, 79 and 107 patients were assigned to the stress and reference groups, respectively. The stress group had more patients with poor outcomes of acute treatment than the reference group (67.1% vs 40.2%, P < 0.001). In a multivariate analysis, female gender (odds ratio [OR] = 3.266, 95% confidence interval [CI] = 1.172-9.103, P = 0.024), the number of headache-free days per month (OR = 0.932, 95% CI = 0.883-0.985, P = 0.012), and BEPSI-K score (OR = 1.667, 95% CI = 1.051-2.643, P = 0.030) predicted poor outcomes of acute treatment. Conclusions. High levels of stress were reported by 42.5% of patients with CM. The association between stress and the outcomes of acute treatment suggests that stress is an important clinical variable for improving the management of CM.
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