Improved reutilization of industrial crude lysine to 1,5-diaminopentane by enzymatic decarboxylation using various detergents and organic solvents
- 주제(키워드) 1 , 5-Diaminopentane , Cadaverine , Decarboxylation , Detergent , Hafnia alvei , Lysine
- 주제(기타) Chemistry, Multidisciplinary; Engineering, Chemical
- 설명문(일반) [Kim, Hanyong; Kim, Yong Hwan; Sohn, Hiesang; Lee, Taek; Park, Chulhwan] Kwangwoon Univ, Dept Chem Engn, 20 Kwangwoon Ro, Seoul 01897, South Korea; [Yoo, Hah Young] Sangmyung Univ, Dept Biotechnol, 20 Hongjimun 2 Gil, Seoul 03016, South Korea; [Kim, Yong Hwan] Ulsan Natl Inst Sci & Technol, Sch Energy & Chem Engn, 50 UNIST Gil, Ulsan 44919, South Korea; [Kim, Il-Kwon] Daesang Co Ltd, Dept Bioproc Res, 697 Jungbudae Ro, Majang Myeon 17384, Gyeonggi, South Korea; [Byun, Eui-Hong] Kongju Natl Univ, Dept Food Sci & Technol, 54 Daehak Ro, Yesan 32439, Chungnam, South Korea; [Yang, Yung-Hun] Konkuk Univ, Dept Biol Engn, 120 Neungdong Ro, Seoul 05029, South Korea; [Park, Si Jae] Ewha Womans Univ, Div Chem Engn & Mat Sci, 52 Ewhayeodae Gil, Seoul 03760, South Korea; [Na, Jeong-Geol] Sogang Univ, Dept Chem & Biomol Engn, 35 Baekbeom Ro, Seoul 04107, South Korea; [Kim, Jung Rae] Pusan Natl Univ, Sch Chem & Biomol Engn, 2 Busandaehak Ro,63 Beon Gil, Busan 46241, South Korea
- 관리정보기술 faculty
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 KOREAN INSTITUTE CHEMICAL ENGINEERS
- 발행년도 2018
- URI http://www.dcollection.net/handler/ewha/000000156901
- 본문언어 영어
- Published As http://dx.doi.org/10.1007/s11814-018-0075-z
초록/요약
World-wide production of l-lysine has rapidly increased in recent years. In the industrial scale production, it is cost effective to minimize waste as many waste materials are generated during downstream processing. Therefore, the conversion of crude lysine to a more valuable product reduces waste emission. In this study, 1,5-diaminopentane (DAP, trivial name: cadaverine) was produced by l-lysine decarboxylation using Hafnia alvei. The conditions of enzymatic reaction were determined. In particular, the addition of specific detergent (Brij 56) was significantly affected in the bioconversion system. Addition of hydrophobic organic solvent improved the mixing of the reactants. Finally, an industrial crude form of lysine served as a substrate. The DAP conversion by analytical, feed and industrial crude l-lysine was 93.9%, 90.3%, and 63.8%, respectively.
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