Cohort profile: Beyond birth cohort study - The Korean CHildren's ENvironmental health Study (Ko-CHENS)
- 주제(키워드) Ko-CHENS , Children , Environment , Cohort profile , Birth cohort
- 주제(기타) Environmental Sciences; Public, Environmental & Occupational Health
- 설명문(일반) [Jeong, Kyoung Sook] Hallym Univ, Sacred Heart Hosp, Dept Occupat & Environm Med, Anyang, South Korea; [Kim, Suejin; Park, Choonghee; Kim, Hyun Jeong; Jung, Soon-Won; Hong, Sooyeon; Jung, A-Ra; Lee, Jueun; Do Yu, Seung] Natl Inst Environm Res, Dept Environm Hlth Res, Environm Hlth Res Div, Minist Environm, Incheon, South Korea; [Kim, Woo Jin; Han, Yuri] Kangwon Natl Univ, Dept Internal Med, Chunchon, South Korea; [Kim, Woo Jin; Han, Yuri] Kangwon Natl Univ, Environm Hlth Ctr, Chunchon, South Korea; [Kim, Hwan-Cheol] Inha Univ, Sch Med, Dept Occupat & Environm Med, Incheon, South Korea; [Bae, Jisuk] Daegu Catholic Univ, Sch Med, Dept Prevent Med, Daegu, South Korea; [Hong, Yun-Chul; Lim, Youn-Hee] Seoul Natl Univ, Med Res Ctr, Inst Environm Med, Seoul, South Korea; [Ha, Mina; Kwon, Ho-Jang; Choi, Kyung-Hwa] Dankook Univ, Coll Med, Dept Prevent Med, Cheonan, South Korea; [Ahn, Kangmo; Kim, Jihyun] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Dept Pediat, Seoul, South Korea; [Ahn, Kangmo; Chun, Se-Jin; Kim, Young-Min; Kim, Jihyun] Sungkyunkwan Univ, Sch Med, Samsung Med Ctr, Environm Hlth Ctr Atop Dis, Seoul, South Korea; [Lee, Ji-Young; Ha, Eunhee; Lee, Myeongjee; Park, Eun Kyo] Ewha Womans Univ, Dept Occupat & Environm Med, Sch Med, Seoul, South Korea; [Kim, Yangho; Lee, Jiho; Sim, Chang Sun] Univ Ulsan, Ulsan Univ Hosp, Coll Med, Dept Occupat & Environm Med, Ulsan, South Korea; [Hwang, Namkyoung; Jeong, Dong Jin; Seo, Heung Won] Minist Environm, Off Environm Hlth, Environm Hlth Policy Div, Sejong, South Korea; [Kim, Hae Soon] Ewha Womans Univ, Dept Pediat, Med Ctr, Seoul, South Korea; [Lee, Seulbi] Ewha Womans Univ, Sch Med, Dept Med Sci, Seoul, South Korea; [Kook, Hoon; Baek, Hee Jo; Moon, Jai Dong; Park, Won Ju; Shin, Myung-Geun] Chonnam Natl Univ, Hwasun Hosp, Environm Hlth Ctr Childhood Leukemia & Canc, Hwasun, South Korea; [Kook, Hoon; Baek, Hee Jo] Chonnam Natl Univ, Hwasun Hosp, Dept Pediat, Hwasun, South Korea; [Moon, Jai Dong; Park, Won Ju] Chonnam Natl Univ, Hwasun Hosp, Dept Occupat & Environm Med, Hwasun, South Korea; [Shin, Myung-Geun] Chonnam Natl Univ, Hwasun Hosp, Dept Lab Med, Hwasun, South Korea; [Paik, Ki-Chung] Dankook Univ, Coll Med, Dept Psychiat, Cheonan, South Korea; [Lim, Myung-Ho] Dankook Univ, Coll Publ Serv, Dept Psychol, Cheonan, South Korea; [Paik, Ki-Chung; Kwon, Ho-Jang; Lim, Myung-Ho; Yoo, Seung Jin] Dankook Univ, Environm Hlth Ctr, Med Ctr, Cheonan, South Korea; [Bae, Sanghyuk] Catholic Univ Korea, Coll Med, Dept Prevent Med, Seoul, South Korea; [Hong, Young-Seoub; Kim, Yu-Mi; Seo, Jeong-Wook] Dong A Univ, Coll Med, Dept Prevent Med, Busan, South Korea; [Hong, Young-Seoub; Kim, Yu-Mi; Seo, Jeong-Wook] Dong A Univ, Coll Med, Heavy Met Exposure Environm Hlth Ctr, Busan, South Korea; [Kim, Myo Jing; Chueh, Hee Won] Dong A Univ, Coll Med, Dept Pediat, Busan, South Korea; [Lim, Dae Hyun; Kim, Jeong Hee; Kim, Donghyun] Inha Univ, Dept Pediat, Sch Med, Incheon, South Korea; [Lim, Dae Hyun; Kim, Jeong Hee; Park, Joohye; Kim, Donghyun; So, Hye Ju] Inha Univ Hosp, Environm Hlth Ctr Allerg Dis, Incheon, South Korea; [Hong, Sung-Chul; Lee, Keun Hwa; Kim, Su-Young] Jeju Natl Univ, Environm Hlth Ctr, Coll Med, Jeju, South Korea; [Hong, Sung-Chul; Kim, Su-Young] Jeju Natl Univ, Dept Prevent Med, Coll Med, Jeju, South Korea; [Lee, Keun Hwa] Jeju Natl Univ, Dept Microbiol & Immunol, Coll Med, Jeju, South Korea; [Na, Sunghun] Kangwon Natl Univ, Kangwon Natl Univ Hosp, Dept Obstet & Gynecol, Sch Med, Chunchon, South Korea; [Noh, Byoungho] Kangwon Natl Univ Hosp, Dept Pediat, Chunchon, South Korea; [Kwon, Sung Ok] Kangwon Natl Univ Hosp, Biomed Res Inst, Chunchon, South Korea; [Choung, Ji Tae; Yoo, Young] Korea Univ, Anam Hosp, Dept Pediat, Seoul, South Korea; [Choung, Ji Tae; Yoo, Young; Seo, Sung Chul; Kang, Hyeonju; Jang, Ji Yeon] Korea Univ, Anam Hosp, Environm Hlth Ctr, Seoul, South Korea; [Jung, Minyoung] Kosin Univ, Gospel Hosp, Sch Med, Dept Pediat, Busan, South Korea; [Lim, Youn-Hee] Seoul Natl Univ, Coll Med, Environm Hlth Ctr, Seoul, South Korea; [Park, Joong Shin; Park, Chan-Wook] Seoul Natl Univ Hosp, Dept Obstet & Gynecol, Seoul, South Korea; [Shin, Choong Ho] Seoul Natl Univ Hosp, Dept Pediat, Seoul, South Korea; [Woo, KuckHyeun] Soonchunhyang Univ, Gumi Hosp, Dept Occupat & Environm Med, Gumi, South Korea; [Choi, SungYong] Soonchunhyang Univ, Gumi Hosp, Environm Hlth Ctr, Gumi, South Korea; [Kim, JinKyung] Daegu Catholic Univ, Sch Med, Dept Pediat, Daegu, South Korea; [Yang, Wonho] Daegu Catholic Univ, Dept Occupat Hlth, Kyongsan, South Korea; [Hur, Jongil; Park, Myung-Sook; Choi, Kyung-Hwa; Lee, Seung-Hwa] Taean Environm Hlth Ctr, Taean, South Korea; [Oh, Inbo] Univ Ulsan, Coll Med, Environm Hlth Ctr, Ulsan, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 ACADEMIC PRESS INC ELSEVIER SCIENCE
- 발행년도 2019
- URI http://www.dcollection.net/handler/ewha/000000159721
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.envres.2018.12.009
- PubMed https://pubmed.ncbi.nlm.nih.gov/30825686
초록/요약
The Korean CHildren's ENvironmental health Study (Ko-CHENS) is a nationwide prospective birth cohort showing the correlation between the environmental exposures and the health effects to prevent the environmental diseases in children, and it provides the guidelines for the environmental hazardous factors, applying the life-course approach to the environmental-health management system. The Ko-CHENS consists of 5000 Core and 65,000 Main Cohorts. The children in the Core Cohort are followed up at 6 months, every year before their admission into the elementary school, and every 3 years from the first year after this admission. The children in the Cohort will be followed up through the data links (Statistics Korea, National Health Insurance Service [NHIS], and Ministry of Education). The individual biospecimens will be analyzed for 19 substances. The long-term-storage biological samples will be used for the further substance analysis. The Ko-CHENS will investigate whether the environmental variables including the perinatal outdoor and indoor factors and the greenness contribute causally to the health outcomes in the children and adolescents. In addition to the individual surveys, the assessments of the outdoor exposures and health outcomes will use the national air-quality monitoring data and claim data of the NHIS, respectively. The two big-data forms of the Ko-CHENS are as follows: The Ko-CHENS data that can be linked with the nationally registered NHIS health-related database, including the medical utilization and the periodic health screening, and the birth/mortality database in the Statistics; the other is the Big-CHENS dataset that is based on the NHIS mother delivery code, for which the follow-up of almost 97% of the total birth population is expected. The Ko-CHENS is a very cost-effective study that fully exploits the existing national big-data systems with the data linkage.
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