Chan-Lam coupling reaction of sulfamoyl azides with arylboronic acids for synthesis of unsymmetrical N-arylsulfamides
- 주제(기타) Chemistry, Multidisciplinary
- 설명문(일반) [Won, Suk-Young; Kim, Seo-Eun; Kwon, Yong-Ju; Kim, Won-Suk] Ewha Womans Univ, Dept Chem & Nanosci, Seoul 03760, South Korea; [Shin, Inji] KRICT, Innovat Therapeut Res Ctr, Therapeut & Biotechnol Div, Daejeon 34602, South Korea; [Shin, Inji] Univ Sci & Technol, Dept Med & Pharmaceut Chem, Daejeon 34101, South Korea; [Ham, Jungyeob] KIST, Nat Prod Res Inst, Kangnung 25451, South Korea
- 등재 SCIE, SCOPUS
- OA유형 Green Published, gold
- 발행기관 ROYAL SOC CHEMISTRY
- 발행년도 2019
- URI http://www.dcollection.net/handler/ewha/000000160258
- 본문언어 영어
- Published As http://dx.doi.org/10.1039/c8ra09219b
- PubMed https://pubmed.ncbi.nlm.nih.gov/35520509
초록/요약
An efficient method was developed for the synthesis of unsymmetrical N-arylsulfamides using sulfamoyl azides and arylboronic acids in the presence of 10mol% of copper chloride as the catalyst. The reaction was facilitated in MeOH in an open flask at room temperature. Unlike the coupling of sulfamides and boronic acids, the use of sulfamoyl azides was found to be beneficial with respect to the yield and reaction time.
more