Heterogeneous living donor hepatic fat distribution on MRI chemical shift imaging
- 주제(키워드) Fatty liver , Liver transplantation , Magnetic resonance imaging , Transplant donor site
- 주제(기타) Surgery
- 등재 SCIE, SCOPUS, KCI등재
- 발행기관 KOREAN SURGICAL SOCIETY
- 발행년도 2015
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000161935
- 본문언어 영어
- Published As http://dx.doi.org/10.4174/astr.2015.89.1.37
초록/요약
Purpose: We evaluated the heterogeneity of steatosis in living donor livers to determine its regional differences. Methods: Between June 2011 and February 2012, 81 liver donors were selected. Fat fraction was estimated using magnetic resonance triple-echo chemical shifting gradient imaging in 13 different regions: segment 1 (S1), S2, S3, and each peripheral and deep region of 54, 55, S6, S7, and S8. Results: There were differences (range, 3.2%-5.3%) in fat fractions between each peripheral and deep region of S4, S6, S7, and 58 (P < 0.001, P = 0.004, P < 0.001, and P = 0.006). Fat deposit amount in Si, S2, S3 and deep regions of S4-S8 were significantly different from one another (F [4.003, 58.032] = 8.684, P < 0.001), while there were no differences among the peripheral regions of S4-S8 (F [2.9, 5.3] = 1.3, P = 0.272) by repeated measure analysis of variance method. And regional differences of the amount of fat deposit in the whole liver increased as a peripheral fat fraction of S5 increased (R-2 = 0.428, P < 0.001). Conclusion: Multifocal fat measurements for the whole liver are needed because a small regional evaluation might not represent the remaining liver completely, especially in patients with severe hepatic steatosis.
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