Combined Outer Volume Suppression and T-2 Preparation Sequence for Coronary Angiography
- 주제(키워드) outer volume suppression , T-2 Prep , cones imaging , radiofrequency pulse design , coronary MR angiography
- 주제(기타) Radiology, Nuclear Medicine & Medical Imaging
- 관리정보기술 faculty
- 등재 SCIE, SCOPUS
- 발행기관 WILEY-BLACKWELL
- 발행년도 2015
- URI http://www.dcollection.net/handler/ewha/000000161989
- 본문언어 영어
- Published As http://dx.doi.org/10.1002/mrm.25575
초록/요약
Purpose: To develop a magnetization preparation sequence for simultaneous outer volume suppression (OVS) and T-2 weighting in whole-heart coronary magnetic resonance angiography. Methods: A combined OVS and T-2 preparation sequence (OVS-T-2 Prep) was designed with a nonselective adiabatic 90 degrees tipdown pulse, two adiabatic 180 degrees refocusing pulses, and a 2D spiral -90 degrees tipup pulse. The OVS-T-2 Prep preserves the magnetization inside an elliptic cylinder with T-2 weighting, while saturating the magnetization outside the cylinder. Its performance was tested on phantoms and on 13 normal subjects with coronary magnetic resonance angiography using 3D cones trajectories. Results: Phantom studies showed expected T-2-dependent signal amplitude in the spatial passband and suppressed signal in the spatial stopband. In vivo studies with full-field-of-view cones yielded a passband-to-stopband signal ratio of 3.18 +/- 0.77 and blood-myocardium contrast-to-noise ratio enhancement by a factor of 1.43 +/- 0.20 (P < 0.001). In vivo studies with reduced-field-of-view cones showed that OVS-T-2 Prep well suppressed the aliasing artifacts, as supported by significantly reduced signal in the regions with no tissues compared to the images acquired without preparation (P < 0.0001). Conclusion: OVS-T-2 Prep is a compact sequence that can accelerate coronary magnetic resonance angiography by suppressing signals from tissues surrounding the heart while simultaneously enhancing the blood-myocardium contrast. (C) 2014 Wiley Periodicals, Inc.
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