Preparation of diisononyl adipate in a solvent-free system via an immobilized lipase-catalyzed esterification
- 주제(키워드) Adipic acid , Diisononyl adipate , Esterification , Eversa lipase , Isononyl alcohol , Plasticizer
- 등재 SCIE, SCOPUS
- 발행기관 Elsevier Inc.
- 발행년도 2019
- URI http://www.dcollection.net/handler/ewha/000000162296
- 본문언어 영어
- Published As http://dx.doi.org/10.1016/j.enzmictec.2019.04.014
- PubMed https://pubmed.ncbi.nlm.nih.gov/31615683
초록/요약
Diisononyl adipate is a plasticizer which has excellent property of low temperature resistance and is permitted in food contact materials. In this study, diisononyl adipate was synthesized from adipic acid and isononyl alcohol in a solvent-free system via immobilized lipase-catalyzed esterification. Liquid Eversa lipase from Thermomyces lanuginosus was immobilized on Lewatit VP OC 1600 carrier. The effects of temperature, substrate molar ratio, water activity of enzyme, vacuum, and enzyme loading on the reaction efficiency were investigated. Application of vacuum played a key role to achieve a 100% conversion. The optimal temperature, molar ratio (adipic acid to isononyl alcohol), water activity of enzyme, vacuum were 50 °C, 1:3, 0.75, 13.3 kPa, and 10% (based on weight of total substrate). Under these conditions, 100% conversion was achieved within 6 h. © 2019 Elsevier Inc.
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