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Impact of the 2017 American Academy of Pediatrics Guideline on Hypertension Prevalence Compared With the Fourth Report in an International Cohort

  • 주제(키워드) blood pressure , child , hypertension , pediatrics
  • 주제(기타) Peripheral Vascular Disease
  • 설명문(일반) [Yang, Liu; Xi, Bo] Shandong Univ, Sch Publ Hlth, Dept Epidemiol, 44 Wenhuaxi Rd, Jinan 250012, Shandong, Peoples R China; [Kelishadi, Roya; Ardalan, Gelayol] Isfahan Univ Med Sci, Res Inst Primordial Prevent Non Communicable Dis, Dept Pediat, Child Growth & Dev Res Ctr, Esfahan, Iran; [Hong, Young Mi; Kim, Hae Soon] Ewha Womans Univ, Dept Pediat, Sch Med, Seoul, South Korea; [Khadilkar, Anuradha; Khadilkar, Vaman; Chiplonkar, Shashi; Kajale, Neha; Ekbote, Veena] Jehangir Hosp, Hirabai Cowasji Jehangir Med Res Inst, Growth & Endocrine Unit, Pune, Maharashtra, India; [Nawarycz, Tadeusz; Ostrowska-Nawarycz, Lidia] Med Univ Lodz, Dept Biophys, Lodz, Poland; [Krzywinska-Wiewiorowska, Malgorzata; Krzyzaniak, Alicja; Stawinska-Witoszynska, Barbara] Poznan Univ Med Sci, Dept Hyg & Epidemiol, Poznan, Poland; [Aounallah-Skhiri, Hajer] Natl Inst Publ Hlth Nutr Surveillance & Epidemiol, Res Lab, Tunis, Tunisia; [Motlagh, Mohammad Esmaeil] Ahvaz Jundishapur Univ Med Sci, Dept Pediat, Ahwaz, Iran; [Ben Romdhane, Habiba] Univ Tunis El Manar, Fac Med, Res Lab, Cardiovasc Epidemiol & Prevent, Tunis, Tunisia; [Heshmat, Ramin] Univ Tehran Med Sci, Endocrinol & Metab Populat Sci Inst, Dept Epidemiol, Chron Dis Res Ctr, Tehran, Iran; [El Ati, Jalila] Natl Inst Nutr & Food Technol, Nutr Surveillance & Epidemiol Unit, Tunis, Tunisia; [Qorbani, Mostafa] Alborz Univ Med Sci, Noncommunicable Dis Res Ctr, Dept Epidemiol, Karaj, Iran; [Traissac, Pierre] UM, SupAgro, IRD, NUTRIPASS,UMR, Montpellier, France; [Zhao, Min] Shandong Univ, Sch Publ Hlth, Dept Nutr & Food Hyg, Jinan, Shandong, Peoples R China; [Heiland, Emerald G.] Swedish Sch Sport & Hlth Sci GIH, Stockholm, Sweden; [Liang, Yajun] Karolinska Inst, Dept Publ Hlth Sci, Stockholm, Sweden
  • 등재 SCIE, SCOPUS
  • OA유형 Bronze
  • 발행기관 LIPPINCOTT WILLIAMS & WILKINS
  • 발행년도 2019
  • 총서유형 Journal
  • URI http://www.dcollection.net/handler/ewha/000000165978
  • 본문언어 영어
  • Published As http://dx.doi.org/10.1161/HYPERTENSIONAHA.119.13807
  • PubMed https://pubmed.ncbi.nlm.nih.gov/31630571

초록/요약

In 2017, the American Academy of Pediatrics (AAP) updated the clinical practice guideline for high blood pressure (BP) in the pediatric population. In this study, we compared the difference in prevalence of elevated and hypertensive BP values defined by the 2017 AAP guideline and the 2004 Fourth Report and estimated the cardiovascular risk associated with the reclassification of BP status defined by the AAP guideline. A total of 47 200 children and adolescents aged 6 to 17 years from 6 countries (China, India, Iran, Korea, Poland, and Tunisia) were included in this study. Elevated BP and hypertension were defined according to 2 guidelines. In addition, 1606 children from China, Iran, and Korea who were reclassified upward by the AAP guideline compared with the Fourth Report and for whom laboratory data were available were 1:1 matched with children from the same countries who were normotensive by both guidelines. Compared with the Fourth Report, the prevalence of elevated BP defined by the AAP guideline was lower (14.9% versus 8.6%), whereas the prevalence of stages 1 and 2 hypertension was higher (stage 1, 6.6% versus 14.5%; stage 2, 0.4% versus 1.7%). Additionally, comparison of laboratory data in the case-control study showed that children who were reclassified upward were more likely to have adverse lipid profiles and high fasting blood glucose compared with normotensive children. In conclusion, the prevalence of elevated BP and hypertension varied significantly between both guidelines. Applying the new AAP guideline could identify more children with hypertension who are at increased cardiovascular risk.

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