Association of pre-operative medication use with unplanned 30-day hospital readmission after surgery in oncology patients receiving comprehensive geriatric assessment
- 주제(기타) Surgery
- 설명문(일반) [Jeon, Min Sun; Jeong, Young Mi; Yee, Jeong; Lee, Byung Koo; Rhie, Sandy Jeong; Gwak, Hye Sun] Ewha Womans Univ, Coll Pharm, 52 Ewhayeodae Gil, Seoul 03760, South Korea; [Jeon, Min Sun; Jeong, Young Mi; Yee, Jeong; Lee, Byung Koo; Rhie, Sandy Jeong; Gwak, Hye Sun] Ewha Womans Univ, Div Life Pharmaceut Sci, 52 Ewhayeodae Gil, Seoul 03760, South Korea; [Jeon, Min Sun; Jeong, Young Mi; Lee, Eunsook] Seoul Natl Univ, Bundang Hosp, Dept Pharm, Seongnam 13620, South Korea; [Kim, Kwang-Il] Seoul Natl Univ, Bundang Hosp, Coll Med, Dept Internal Med, Seongnam 13620, South Korea; [Chung, Jee Eun] Hanyang Univ, Coll Pharm, 55 Hanyangdeahak Ro, Ansan 15588, Gyeonggido, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 EXCERPTA MEDICA INC-ELSEVIER SCIENCE INC
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000168900
- 본문언어 영어
- Published As https://dx.doi.org/10.1016/j.amjsurg.2019.06.020
- PubMed https://pubmed.ncbi.nlm.nih.gov/31255260
초록/요약
Background: This study aimed to determine whether pre-operative medication use is associated with unplanned 30-day readmission in elderly people undergoing cancer surgery. Methods: Patients aged 65 years or older who were scheduled for cancer surgery and presented for comprehensive geriatric assessment were included. Comparisons of variables between patients with readmission and those without readmission were performed by univariate and multivariate analyses. Results: A total of 473 patients were included. Multivariate analysis showed that pre-operative discontinuation-requiring medications (PDRMs) and gastrointestinal/hepato-pancreato-biliary (GI/HPB) cancer were significant factors for 30-day readmission. PDRM increased the risk of readmission by about 2.2-fold. Attributable risk of PDRM to readmission was around 55%. The adjusted odds ratio and attributable risk for GI/HPB surgery was 3.4 (95% CI 1.0-11.5) and 70.8%, respectively. Conclusions: Medication use has an impact on unplanned 30-day readmission in geriatric oncology patients, further highlighting the importance of medication optimization for elderly patients with cancer surgery. (C) 2019 Elsevier Inc. All rights reserved.
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