Predicting Stroke Outcomes Using Ankle-Brachial Index and Inter-Ankle Blood Pressure Difference
- 주제(키워드) ankle-brachial index difference , inter-ankle blood pressure difference , stroke , peripheral artery disease , outcome
- 주제(기타) Medicine, General & Internal
- 설명문(일반) [Han, Minho; Kim, Young Dae; Choi, Jin Kyo; Choi, Junghye; Ha, Jimin; Heo, Ji Hoe; Nam, Hyo Suk] Yonsei Univ, Dept Neurol, Coll Med, Seoul 03722, South Korea; [Kim, Young Dae; Heo, Ji Hoe; Nam, Hyo Suk] Integrat Res Ctr Cerebrovasc & Cardiovasc Dis, Seoul 03722, South Korea; [Park, Eunjeong] Yonsei Univ, Cardiovasc Res Inst, Coll Med, Seoul 03722, South Korea; [Kim, Jinkwon] Yonsei Univ, Yongin Severance Hosp, Dept Neurol, Coll Med, Yongin 16995, South Korea; [Song, Tae-Jin] Ewha Womans Univ, Seoul Hosp, Dept Neurol, Coll Med, Seoul 07804, South Korea
- 등재 SCIE, SCOPUS
- OA유형 Green Published, gold
- 발행기관 MDPI
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000169382
- 본문언어 영어
- Published As https://dx.doi.org/10.3390/jcm9041125
- PubMed https://pubmed.ncbi.nlm.nih.gov/32326413
초록/요약
Background: This study investigated the association of high ankle-brachial index difference (ABID) and systolic inter-ankle blood pressure difference (IAND) with short- and long-term outcomes in acute ischemic stroke patients without peripheral artery disease (PAD). Methods: Consecutive patients with acute ischemic stroke who underwent ankle-brachial index (ABI) measurement were enrolled. ABID was calculated as
more초록/요약
. Poor functional outcome was defined as modified Rankin Scale score >= 3 at 3 months. Major adverse cardiovascular events (MACEs) were defined as stroke recurrence, myocardial infarction, or death. Results: A total of 2901 patients were enrolled and followed up for a median of 3.1 (interquartile range, 1.6-4.7) years. Among them, 2643 (84.9%) patients did not have PAD. In the logistic regression analysis, ABID >= 0.15 and IAND >= 15 mmHg were independently associated with poor functional outcome (odds ratio (OR), 1.970, 95% confidence interval (CI), 1.1753.302; OR, 1.665, 95% CI, 1.1882.334, respectively). In Cox regression analysis, ABID >= 0.15 and IAND >= 15 mmHg were independently associated with MACEs (hazard ratio (HR), 1.514, 95% CI, 1.0582.166; HR, 1.343, 95% CI, 1.0511.716, respectively) and all-cause mortality (HR, 1.524, 95% CI, 1.0392.235; HR, 1.516, 95% CI, 1.1641.973, respectively) in patients without PAD. Conclusion: High ABID and IAND are associated with poor short-term outcomes, long-term MACE occurrence, and all-cause mortality in acute ischemic stroke without PAD.
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