A self-powered insulin patch pump with a superabsorbent polymer as a biodegradable battery substitute
- 주제(기타) Materials Science, Biomaterials
- 설명문(일반) [Shao, Jiaying; Chua, Beelee] Korea Univ, Sch Elect Engn, 145 Anam Ro, Seoul 02841, South Korea; [Li, King Ho Holden] Nanyang Technol Univ, Sch Mech & Aerosp Engn, 50 Nanyang Ave,Block N3, Singapore 639798, Singapore; [Son, Ahjeong] Ewha Womans Univ, Dept Environm Sci & Engn, 52 Ewhayeodae Gil, Seoul 03760, South Korea; [Chua, Beelee] Korea Univ, 145 Anam Ro, Seoul 02841, South Korea
- 등재 SCIE, SCOPUS
- 발행기관 ROYAL SOC CHEMISTRY
- 발행년도 2020
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000169593
- 본문언어 영어
- Published As https://dx.doi.org/10.1039/d0tb00385a
- PubMed https://pubmed.ncbi.nlm.nih.gov/32285906
초록/요약
Highly popular insulin patch pumps have in-built non-removable batteries. These batteries are routinely disposed of together with the used pumps as medical waste and end up in landfills. This is an environmental contamination conundrum by design. To address this issue, we proposed a self-powered patch pump that uses a biodegradable superabsorbent polymer (SAP) instead of a battery as a power source to drive the infusion. Continuous infusion rates from 6.1 mu L min(-1) to 49.1 mu L min(-1) were achieved. Together with valve throttling, basal and bolus infusion rates of similar to 10 mu L h(-1) (1 U h(-1)) and 100 mu L (10 U) in similar to 11 min could also be implemented for glycemic control. The generated pressure at similar to 0.7 psi is also adequate for infusion as it exceeded an adult's maximum peripheral venous pressure of 0.6 psi. Given the current number of patch pump users, the proposed design could prevent similar to 100 000 used batteries from entering the medical waste stream and landfill daily. Most importantly, this work highlights the possibility of addressing environmental contamination without compromising on healthcare standards by using SAP as an alternative means of energy storage.
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