Effectiveness of Exercise Intervention in Reducing Body Weight and Glycosylated Hemoglobin Levels in Patients with Type 2 Diabetes Mellitus in Korea: A Systematic Review and Meta-Analysis
- 주제(키워드) Body weight , Exercise therapy , Glycated hemoglobin A , Meta-analysis , Review
- 주제(기타) Endocrinology & Metabolism
- 설명문(일반) [Jang, Ji-Eun] Ewha Womans Univ, Dept Med Sci, Grad Sch, Seoul, South Korea; [Jang, Ji-Eun] Korean Med Assoc, Res Inst Healthcare Policy, Seoul, South Korea; [Cho, Yongin; Lee, Byung Wan] Yonsei Univ, Dept Internal Med, Coll Med, Seoul, South Korea; [Shin, Ein-Soon] Korean Acad Med Sci, Res Ctr, Res Agcy Clin Practice Guidelines, Seoul, South Korea; [Lee, Sun Flee] Ewha Womans Univ, Dept Prevent Med, Sch Med, Seoul, South Korea
- 등재 SCIE, SCOPUS, KCI등재
- OA유형 gold, Green Published, Green Submitted
- 발행기관 KOREAN DIABETES ASSOC
- 발행년도 2019
- 총서유형 Journal
- URI http://www.dcollection.net/handler/ewha/000000171920
- 본문언어 영어
- Published As https://dx.doi.org/10.4093/dmj.2018.0062
- PubMed https://pubmed.ncbi.nlm.nih.gov/30604592
초록/요약
Background: This study aimed to assess the effectiveness of exercise intervention in reducing body weight and glycosylated hemoglobin (HbA1c) level in patients with type 2 diabetes mellitus (T2DM) in Korea. Methods: Cochrane, PubMed, Embase, KoreaMed, KMbase, NDSL, KCI, RISS, and DBpia databases were used to search randomized controlled trials and controlled clinical trials that compared exercise with non-exercise intervention among patients with non-insulin-treated T2DM in Korea. The effectiveness of exercise intervention was estimated by the mean difference in body weight changes and HbA1c level. Weighted mean difference (WMD) with its corresponding 95% confidence interval (CI) was used as the effect size. The pooled mean differences of outcomes were calculated using a random-effects model. Results: We identified 7,692 studies through literature search and selected 23 articles (723 participants). Compared with the control group, exercise intervention (17 studies) was associated with a significant decline in HbA1c level (WMD, -0.58%; 95% CI, -0.89 to -0.27; I-2=73%). Although no significant effectiveness on body weight was observed, eight aerobic training studies showed a significant reduction in body weight (WMD, -2.25 kg; 95% CI, -4.36 to -0.13; I-2=17%) in the subgroup analysis. Conclusion: Exercise significantly improves glycemic control; however, it does not significantly reduce body weight. Aerobic training can be beneficial for patients with non-insulin-treated T2DM in Korea.
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